| 云南克山病病区儿童血浆及尿中激素的测定 |
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| 引用本文： | 李广元,郑纯礼,刘韵辉,宋长锁,李鸿儒,卜昕.云南克山病病区儿童血浆及尿中激素的测定[J].西安交通大学学报(医学版),1989(2). |
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| 作者姓名： | 李广元 郑纯礼 刘韵辉 宋长锁 李鸿儒 卜昕 |
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| 作者单位： | 西安医科大学中西医结合研究所
(李广元，李鸿儒)，西安医科大学第二附属医院中心实验室
(郑纯礼，宋长锁)，陕西省地方病防治研究所
(刘韵辉)，西安医科大学中西医结合研究所(卜昕) |
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| 摘 要： | 1984～1986年,云南楚雄克山病综合考察,测定了该病区儿童或病人肾上腺皮质激素的变化。病区儿童尿中醛固酮、17-羟皮质类固醇、17-酮类固醇偏高,此可能是代偿性的应激改变。病区儿童血浆中胰岛素、C-肽及生长素含量均较对照组降低,此可能为病区因子(包括低硒因素)影响了腺体的结构或/和功能,进而涉及机体物质代谢。
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| 关 键 词： | 激素 放射免疫法 克山病 |
DETERMINATION OF CHILDREN PLASMA AND URINE HORMONES IN YUNAN KESHAN DISEASE AREA |
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| Li Guangyuan,et al.DETERMINATION OF CHILDREN PLASMA AND URINE HORMONES IN YUNAN KESHAN DISEASE AREA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1989(2). |
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| Authors: | Li Guangyuan |
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| Institution: | Institute of Inteuted Traditional Chinese and Western Medicine |
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| Abstract: | A comprehensive survey of Keshan disease inChuxiong state,Yunan province,was carried out in1984～1986.The contents of urine aldosterone,17-hydroxycorticosteroids and 17-ketosteroid inchildren were determined by radiommunassay.Theirlevels were higher than in controls.This might be achange due to compensary stress.The plasma insulin,C-peptide and growth hormone contents werealso measured by radicimmunoassay,and they werelower than in controls.It is possible that disease areafactors(including the selenium eficient factor)haddamaged the construction of/and function of incretoryglands,acconrdingly affecting the metabolism in thebody. |
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| Keywords: | hormone radioimmunoassay keshan disease |
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