心肌保护-在心脏停跳期间右心房壁的酶学变化

本文研究了连续9例心内直视手术患者在心脏停跳期间右心房壁心肌酶(CPK、CPK-MBLDH)的变化,同时观察了血清酶的变化。结果表明用晶体心脏停跳液、全身中度低温及局部深低温保护心肌可使心房得到满意的保护。心脏停跳前和复跳前心房酶的变化无统计学上的差异。本文还讨论了用心房酶作为反映心肌保护程度的指标的意义。认为心肌酶的变化能够较好地反映心肌在心脏停跳期间的代谢活动,有临床使用价值。

MYOCARDUAL PROTECTION——THE ENZYMATIC CHANGES OF THE RIGHT ATRIAL WALL DURING CARDIOPLEGIC ARREST

The authors studied the changes of myocardial enzymes (CPK, CPK-MB, LDH) in the wall of the right atrium during cardioplegic arrest in ninsecutive patients who had an open heart operation, observed the changes of these enzymes in seium as well The results indicate that when the crystalloid cardioplegic solution, systemic moderate hypothermia and decp local hypothermia are used to protect the myocardium, the right atrium can get satisfactory protection during cardioplegic arrest and there is no statistical differences of enzyme changes between samples taken from the right atrium before and after the arrest. The article still discussed the possibility of using the changes of atrial myocardial enzymes as an index to reflect the extent of myocardial protion. The authors consider that the change of myocardial enzyme can better reflect the metabolic activity of myocardium during cardioplegic arrest.