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POLYMORPHISM OF THE vWF LOCUS AND ITS FORENSIC APPLICATION IN COMPACT BONE
作者姓名:杨武  李生斌  赖淑苹  赖江华  武永飞
作者单位:Immunogenetic Center,Xi'an Medical University,Xi'an 710061
摘    要:Amplifiedfragmentlengthpolymorphisms(Amp--FLPs)havebeenevaluatedasusefulgeneticmarkersinforensiccaseworks{'~'].vWFpolymorphismisoneoftheAmp--FLPsdetectedbythepolymerasechainreaction(PCR).-PopulationdataconcerningvWFhasbeedpreviouslycarriedoutonEuropeanCaucasians13.ButnodataisavailablefortheChinesepopulation.Inthisreport,wepresentthedataforvWFlocusin112unrelatedChineseHanindividualsanditsapplicabilityincompactboneanddens.MATERIALSANDMETHODS1.PrimersA:5'~ACGTATTCTATTTAT~3…


POLYMORPHISM OF THE vWF LOCUS AND ITS FORENSIC APPLICATION IN COMPACT BONE.
Yang Wu, Li Shengbin, Lai Shuping, Lai Jianghua,Wu Yongfei.POLYMORPHISM OF THE vWF LOCUS AND ITS FORENSIC APPLICATION IN COMPACT BONE[J].Academic Journal of Xi’an Jiaotong University,1998(1).
Authors:Yang Wu  Li Shengbin  Lai Shuping  Lai Jianghua  Wu Yongfei
Abstract:The allele rrequencles or the vWF locus were determined in a chinese Han populationsample (n=112) using the polymerase chain reaction (PCR). 7 alleies and 23 genotypes were observed. Distribution of allellc frequencies in our data showed a different pattern from those reportedin the literature ror European Caucasians. No deviation from Hardy--Weinberg equilibrium wasfound. The observed heterozygoslty was 79. I %. The vWF Is one of the useful genetic markers forpaternity testing and identity testing, with an exclusion power (EP) value or 0. 7337 and a discrimination power (DP) value of 0. 9438. The results of compact bone and dens were in perrect agreementwith those of the blood and blood stains.
Keywords:short tandem repeats  vWF  Amp-FLP  compact bone  chinese Han population
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