| 镓盐对去势大鼠骨质疏松骨结构的影响 |
| |
| 引用本文： | 庞炜,王治伦,吕旌乔,李广元,邸明芝.镓盐对去势大鼠骨质疏松骨结构的影响[J].西安交通大学学报(医学版),2000,21(5):415-416. |
| |
| 作者姓名： | 庞炜 王治伦 吕旌乔 李广元 邸明芝 |
| |
| 作者单位： | 解放军323医院，西安710054 |
| |
| 摘 要： | 目的 了解镓盐对骨质疏松症的治疗作用进行了以大鼠对象的实验研究。方法 实验分两步进行，首先去除成年大鼠卵巢，复制骨质疏松模型；然后应用镓盐进行治疗。采用骨强度测定和骨病理形态学方法观察骨结构的改变情况。结果 ①骨质疏松组与对照组相比各指标均下降，差异具有统计学意义；②镓治疗组与骨质疏松组相比，骨吸收的病理变化减轻，差异具有统计学意义，骨强度亦有提高的趋势。结论 镓盐对骨质疏松症有治疗或减缓其进程的作用。
|
| 关 键 词： | 骨质疏松症 镓盐 骨强度 |
| 文章编号： | 0258-0659(2000)05-0415-02 |
| 修稿时间： | 2000年3月30日 |
The effect of gallium salt on preventing and treating osteoporosis |
| |
| Abstract: | Objective To acquire the effect of gallium salt on preventing and treating osteoporo sis. Methods The experiment was composed of two steps:①Duplicating an animal model of osteo porosis; ②Treating the rats with gallium salt. Results ①All the experimental parameters of osteo porosis decreased and had significant difference compared to those of the controls;②The pathologic bone resorption changes in therapeutic group are alleviated and have significant difference in compar ison to control group. The bone intensity also appeared an improving trend. Conclusion Gallium salt has therapeutic effect on osteoporosis or is able to retard the progress of this disease. |
| |
| Keywords: | osteoporosis gallium salt bone intensity |
| 本文献已被 万方数据 等数据库收录！ |
