| 淫羊藿总黄酮对家兔血液流变学指标的影响 |
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| 引用本文： | 高其铭,袁秉祥,赵苏玉,李生正,刘次伯.淫羊藿总黄酮对家兔血液流变学指标的影响[J].西安交通大学学报(医学版),1992(3). |
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| 作者姓名： | 高其铭 袁秉祥 赵苏玉 李生正 刘次伯 |
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| 作者单位： | 西安医科大学药学系药理教研室，西安医科大学药学系药理教研室，西安老年病医，西安医科大学药学系有机化学教研室，西安医科大学药学系有机化学教研室 西安 710061，西安 710061 |
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| 摘 要： | 研究淫羊藿总黄酮(FEBM)对家兔血液流变学指标的影响,结果表明:FEBM在0.1g/kg或0.4g/kg时,每天两次灌胃,连续3d,可抑制家兔体外血栓形成;在0.4g/kg时可降低2～40s~(-1)切变率时的全血粘度和抑制红细胞的聚集。实验说明FEBM抑制血栓形成的主要因素可能和降低红细胞聚集性及降低全血粘度有关。
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| 关 键 词： | 淫羊藿总黄酮 血液流变学 兔 |
EFFECTS OF FLAVONES OF EPINEDIUM BREVICORNUM MAXIM ON HEMORRHEOLOGICAL PARAMETERS OF RABBITS |
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| Gao Qiming,Yuan Bingxiang,Liu Cibo,.EFFECTS OF FLAVONES OF EPINEDIUM BREVICORNUM MAXIM ON HEMORRHEOLOGICAL PARAMETERS OF RABBITS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(3). |
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| Authors: | Gao Qiming Yuan Bingxiang Liu Cibo |
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| Institution: | Dept. Pharmacology |
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| Abstract: | The effects of flavones of epinedium brevicornum maxim (FEBM) on hemorrheological Parameters of rabbits were studied. It was found that FEBM at 0.1 or 0.4g·kg~(-1)·d~(-1)ig b. i. d. could inhibit thrombosis in vitro,at 0.4 g·kg~(-1)· d~(-1) could reduce blood mucosity at 2～40 s~(-1) shearing and inhibit agglutination of red cells. It was demonstrated that the inhibition of thrombosis and the reduction of blood mucosity might be due to the effects of FEBM on agglutination of red cells. |
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| Keywords: | total flavones of epinedium brevicornum maxim hemorrheology rabbit |
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