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绞股蓝总皂甙对犬心血管系统作用的实验研究
引用本文:孔祥蓁,赵树仲,徐世铭. 绞股蓝总皂甙对犬心血管系统作用的实验研究[J]. 西安交通大学学报(医学版), 1988, 0(2)
作者姓名:孔祥蓁  赵树仲  徐世铭
作者单位:西安医科大学机能实验中心(孔祥蓁,赵树仲),安康地区药品检验所(徐世铭)
摘    要:实验观察了绞股蓝总甙对开胸麻醉犬心血管系统的作用。iv绞股蓝总甙1mg/kg后,BP、LVSP及±dp/atmax显著上升;iv绞股蓝总甙20mg/kg后,HR、BP、LVSP、+dP/dtmax、CI、V_(CE)—+dp/dtmax明显下降。结果提示;iv绞股蓝总甙引起血压及心脏功能的变化可因剂量不同而反应不同。


AN EXPERIMENTAL STUDY OF EFFECTS OF JIAOGULANOSIDE ON THE CANINE CARDIOVASCULAR SYSTEM
Kong Xiangzhen,. AN EXPERIMENTAL STUDY OF EFFECTS OF JIAOGULANOSIDE ON THE CANINE CARDIOVASCULAR SYSTEM[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1988, 0(2)
Authors:Kong Xiangzhen  
Affiliation:Center of Functional Laboratory
Abstract:The effects of Jiaogulanoside on the cardiovascular system were observed anesthetized chest-opened dogs,JS lmg/kg iv significantly increased BP, LVSP and ±dP/dt_(max); 20mg/kg iv significantly decreased HR, BP, LVSP, +dP/dt_(max),CI, V_(CE)-- +dP/dt_(mxa), These results suggested that the changes of BP and cardiac function was varied with the different doses of JS.
Keywords:jiaogulanoside  cardiovascular system  heart functional tests  dogs
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