| 单纯性肥胖儿童免疫功能的研究 |
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| 引用本文： | 雷春莲. 单纯性肥胖儿童免疫功能的研究[J]. 西安交通大学学报(医学版), 1995, 0(4) |
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| 作者姓名： | 雷春莲 |
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| 作者单位： | 西安第一附属医院儿科 |
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| 摘 要： | 使用流式细胞仪（ＦＣＭ）对１２名单纯性肥胖症儿童及２０名正常儿童进行了９项淋巴细胞亚群检测对比，结果发现肥胖症儿童ＣＤ３＋细胞、ＣＤ４＋细胞及ＣＤ４＋／ＣＤ８＋之比明显降低（Ｐ＜０．０１）；ＣＤ１９＋细胞、ＣＤ５６＋细胞、ＨＬＡ－ＤＲ＋细胞均出现有意义的升高；ＣＤ８＋细胞、ＣＤ２５＋细胞、ＣＤ５７＋细胞虽较正常儿童有所升高，但经统计学处理无明显差异。检测结果表明：单纯性肥胖儿童的免疫功能有较明显紊乱。提示肥胖症儿童的脂肪酸摄取过剩对免疫功能有一定损害。
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| 关 键 词： | 肥胖；免疫功能；流式细胞仪 |
STUDIES OF IMMUNOLOGICAL FUNCTION IN SIMPLE OBESE CHILDREN |
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| Lei Chunlian. STUDIES OF IMMUNOLOGICAL FUNCTION IN SIMPLE OBESE CHILDREN[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1995, 0(4) |
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| Authors: | Lei Chunlian |
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| Abstract: | different types lymphocyte subsets in peripheral blood were examined by flow cytometry in 12 simple obese children and a normal group which consists of 20 healthy children. The results showed that compared with normal children the simple obese children had significant low CD3 cell, CD4 cell and CD4 /Cd3 (P<0.01).CD19 cell, CD56 cell,HLA-DR cell increased meaningfully.The results show: Obese children were associated with the disorders of immune system,especially cellular immunological hypofunction. This indicates that immunological function can be damaged to a certain extent in obese children who uptake more fatty acid. |
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| Keywords: | obesity immunological function flow cytometry |
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