| 同侧肾缺血及对侧肾切除时留存肾DNA合成的研究 |
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| 引用本文： | 岳金声,常江平,WillamF.F.同侧肾缺血及对侧肾切除时留存肾DNA合成的研究[J].西安交通大学学报(医学版),1995(2). |
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| 作者姓名： | 岳金声 常江平 WillamF.F |
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| 作者单位： | 第一临床医学院传染科，第一临床医学院传染科，Dept.ofNephrology，theUniversityofNorthCarolina 西安710061，西安710061，美国 |
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| 摘 要： | 幼年小白鼠经体内~3H-TdR参入法液闪测定,检测一侧肾缺血及对侧肾切除后留存肾DNA合成的影响。结果表明:肾缺血、肾切除24h后均促进留存肾DNA合成。而一侧肾缺血同时对侧肾切除留存肾脏~3H-TdR参入量升高最明显。并探讨了一侧肾缺血及对肾切除后留存肾的代偿机理。
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| 关 键 词： | 肾缺血 肾切除 肾DNA合成 |
STUDIES ON DNA SYNTHESIS OF REMAINING KIDNEY IN UNILATERAL RENAL ISCHEMIA AND CONTRALATERAL NEPHRECTOMY |
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| Yue Jinsheng,Willam F F,Chang Jiangping.STUDIES ON DNA SYNTHESIS OF REMAINING KIDNEY IN UNILATERAL RENAL ISCHEMIA AND CONTRALATERAL NEPHRECTOMY[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1995(2). |
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| Authors: | Yue Jinsheng Willam F F Chang Jiangping |
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| Abstract: | We employed male Sprague-Dawaly rats by incorporating tritiated thymidine into rats and determined DNA synthesis of remaining kidney in unilateral renal ischemia and contralateral nephrectomy. The result showed that both renal ischemia and nephrectomy after 24h promoted DNA-synthesis of remaining kidney, but incorporating tri-tiated thymidine dose of remaining kidney was markedly elevated in unilateral renal ischemia and contralateral nephrectomy. Through this research, the compensatory machanism of remaining kidney was revealed in unilateral renal ischemia and contralateral nephrectomy. |
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| Keywords: | renal ischemia nephrectomy DNA-synthesis |
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