| 斑蝥素中毒大鼠酶化学研究(Ⅰ)——NADHD及CCO的组织化学观察 |
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| 引用本文： | 刘振山,刘明俊,路卫星.斑蝥素中毒大鼠酶化学研究(Ⅰ)——NADHD及CCO的组织化学观察[J].西安交通大学学报(医学版),1993(2). |
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| 作者姓名： | 刘振山 刘明俊 路卫星 |
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| 作者单位： | 西安医科大学法医病理学教研室，西安医科大学法医病理学教研室，西安医科大学法医病理学教研室 西安 710061 硕士生 黑龙江牡丹江市公安局，西安 710061，西安 710061 |
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| 摘 要： | 本实验对急性斑蝥素染毒大鼠的心、胃及小肠进行了还原型尼克酰胺腺嘌吟二核苷酸脱氢酶(NADHD)和细胞色素氧化酶(CCO)组织化学的实验观察。结果表明,染毒大鼠这三种组织的NADHD和CCO与对照组相比,酶反应颗粒均减少,着色变淡,分布稀疏。提示斑蝥素可使其活性受到不同程度的抑制。
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| 关 键 词： | 斑蝥素 还原型尼克酰胺腺嘌呤二核苷酸脱氢酶(NADHD) 细胞色素氧化酶(CCO) 组织化学 |
STUDY ON THE ENZYMATIC CHEMISTRY IN CANTHARIDIN POISONED RATS (I)——THE HISTOCHEMISTRY OBSERVATION OF NADHD AND CCO |
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| Liu Zhenshan,Liu Mingjun,Lu Weixing.STUDY ON THE ENZYMATIC CHEMISTRY IN CANTHARIDIN POISONED RATS (I)——THE HISTOCHEMISTRY OBSERVATION OF NADHD AND CCO[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1993(2). |
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| Authors: | Liu Zhenshan Liu Mingjun Lu Weixing |
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| Institution: | Liu Zhenshan;Liu Mingjun;Lu Weixing Department of Forensic Pathology |
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| Abstract: | In Cantharidin-poisoned rats, nicotinamide-adenine dinucletide dehydrogenase (NADHD) andcytochrome oxidase (CCO) activities of myocardi-um, stomach and intestine were observed in exper-iment histochemically. The result showed thatNADHD and CCO reaction granules were de-creased, stained weakly, and distributed sparselyin myocardium, stomach and intestine of intoxicat-ed rats as compared with the control group. Thus,from the experimental result it was considered thatcantharidin may inhibit the activities of NADHDand CCO in varving degrees. |
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| Keywords: | cantharidin nicotinamide adenine dinucleotide dehydrogenase (NADHD) cytochrome oxidase (CCO) histochemistry |
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