| 脑脊液脑型肌酸激酶同工酶测定对急性颅脑损伤预后的价值 |
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| 引用本文： | 师蔚,刘守勋,陈泽寰.脑脊液脑型肌酸激酶同工酶测定对急性颅脑损伤预后的价值[J].西安交通大学学报(医学版),1992(4). |
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| 作者姓名： | 师蔚 刘守勋 陈泽寰 |
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| 作者单位： | 西安医科大学第一附属医院神经外科，西安医科大学第一附属医院神经外科，西安医科大学第一附属医院神经外科 西安 710061，西安 710061，西安 710061 |
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| 摘 要： | 本文采用层析荧光法测定了62例急性颅脑损伤患者伤后当天的CSF-CK-BB活性,并与伤后6个月预后按GOS分级的关系作了对比分析。结果表明,急性颅脑损伤患者伤后早期CSF-CK-BB活性测定可作为估价颅脑损伤预后的客观指标,同时结合GCS评分,对提高判断颅脑损伤患者神经功能恢复的准确性有一定参考价值。
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| 关 键 词： | 急性颅脑损伤 脑脊液 肌酸激酶同工酶 预后 |
THE VALUE OF MEASURING CREATINE KINASE BB ACTIVITY IN CEREBROSPINAL FLUID FOR THE OUTCOME FOLLOWING ACUTE HEAD INJURY |
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| Shi Wei,Liu Shouxun,Chen Zehuan.THE VALUE OF MEASURING CREATINE KINASE BB ACTIVITY IN CEREBROSPINAL FLUID FOR THE OUTCOME FOLLOWING ACUTE HEAD INJURY[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(4). |
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| Authors: | Shi Wei Liu Shouxun Chen Zehuan |
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| Abstract: | The brain—type creatine kinase isoenzyme (CK—BB)in the cerebrospinal fluid(CSF) within 24 hs following trauma was measured in 62 cases with acute head injuries by chromatography and fluorometry, and the comparative analysis was made between CSF-CK-BB activities and the outcome of the patients in 6 months after trauma according to Glasgow Outcome Scale(GOS),The results showed that the determinations of CSF-CKBB activities,in combination with Glasgow coma Scale (GCS) can be used as an early objective diagnostic index for assessing the prognosis ,and there was a reference value for improving accuracy of evaluating recovery of neurological disfunction in the patients with acute head injuries. |
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| Keywords: | acute head injury cerebrospinal fluid creatine kinase inoenzyme prognosis |
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