| 甲状腺癌和雌、孕激素受体的研究 |
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| 引用本文： | 谷俊朝,赵洪勋,张一亥,秦兆寅.甲状腺癌和雌、孕激素受体的研究[J].西安交通大学学报(医学版),1997(4). |
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| 作者姓名： | 谷俊朝 赵洪勋 张一亥 秦兆寅 |
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| 作者单位： | 西安第二临床医学院普外科!西安710004(谷俊朝，秦兆寅)，西安第一临床医学院普外科!西安710004(赵洪勋，张一亥) |
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| 摘 要： | 利用酶联亲和组化法检测80例甲状腺良恶性肿瘤雌、孕激素受体（ER，PR）。结果显示：ER，PR阳性率与肿瘤良恶性、分化程度、性别有关。提示：ER，PR可作为甲状腺癌的一个生物学标记，有助于预后判断。ER是影响女性甲状腺癌发病率的一个重要因素，ER，PR阳性细胞可为进一步研究雌、孕激素对甲状腺肿瘤的作用机制提供一个线索。
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| 关 键 词： | 甲状腺癌 雌激素受体 孕激素受体 酶联亲和组化法 |
STUDY OF ESTROGEN AND PROGESTERONE RECEPTOR IN THYROID CANCER |
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| Gu Junchao, Zkao Hongxun, Zhang Yihai et al.STUDY OF ESTROGEN AND PROGESTERONE RECEPTOR IN THYROID CANCER[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1997(4). |
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| Authors: | Gu Junchao Zkao Hongxun Zhang Yihai |
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| Abstract: | Estrogen receptor (ER ) and progesterone receptor(PR) were rneasured using enzymelinked histochemical technique in 80 specimens of thyroid neoplasma. Results of this study showed that sex. nature and grade of neoplasma were the factors influencing the positive rates of ER and PR.It's indicated that detected ER and PR can be used as biological makers, in aid of the choice of clinicalprognosis, endocrinotherapy and the judgtnent of patients. Observed sex differences regarding thyroid tumor incidence may reflect the higher ER and PR positive rates of females. The ER-Positive tumor cell lines are useful for studying the direct effect of estroqen on thvroid tumors. |
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| Keywords: | thyroid carcinoma estrogen receptor progesterone receptor enzyme-linked estrogen (or progesteron) affinity histochemistry method |
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