沙眼衣原体感染与女性不孕的关系

目的　探讨生殖道沙眼衣原体感染与女性不孕的关系。方法　采用聚合酶链反应 (PCR)技术对 2 0 0例不孕患者及 10 0例正常生育者进行沙眼衣原体及解脲支原体 (UU)检测 ,并进行Logistic回归分析。结果　不孕组沙眼衣原体感染阳性率 (33.0 % )明显高于对照组 (10 .0 % ,P <0 .0 1)。经治疗后 ,沙眼衣原体检测转阴者妊娠率 (5 4 .90 % )明显高于未转阴者 (11.11% ,P <0 .0 5 )。同时证实沙眼衣原体感染与不孕、UU感染、宫颈糜烂相关 (P <0 .0 1)。结论　生殖道沙眼衣原体感染是引起不孕的因素之一。对不孕夫妇进行沙眼衣原体常规检查并及时治疗非常必要

The relationship between chlamydia trachomatis infection and infertility

Objective To examine the relationship between chlamydia trachomatis (CT) infection and infertility. Methods We examined 200 infertile patients and 100 normal fertile women by polymerase chain reaction (PCR). Logistic regression analysis was made. Results The positive rate of CT infection in infertile group was 33.0%, while in the control group it was 10.0% with significant differences between the two groups (P<0.01). After treatment, the pregnancy rate of the patients with negative CT infection was higher than that of those whose CT infection remained positive (P<0.05). Meanwhile it was confirmed that CT infection was associated with infertility, ureaplasma ureatylicum (UU) infection and cervical erosion(P< 0.01). Conclusion Infection with CT in the genital tract is one of the factors causing infertility. It is necessary for the infertile couple to receive routine examination and treatment in time.