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虎杖的化学成分之一——蒽醌对心血管系统的作用
引用本文:方秋文,李霞,许苏英,赵更生.虎杖的化学成分之一——蒽醌对心血管系统的作用[J].西安交通大学学报(医学版),1982(4).
作者姓名:方秋文  李霞  许苏英  赵更生
作者单位:西安医学院药理教研室学生科研小组,西安医学院药理教研室学生科研小组,西安医学院药理教研室学生科研小组,西安医学院药理教研室学生科研小组 付教授
摘    要:1.蒽醌注射液对麻醉兔有明显降压作用。连续给药几次后,药量蓄积,小剂量即可引起血压骤降甚至死亡。是否与降低血糖,或药物蓄积中毒有关尚需进一步探讨。2.蒽醌注射液对麻醉兔有明显减慢心率作用,未发现心电图有其它改变。


Effect of Anthraquinone (One of Chemical Compositions of Polygonum Cuspidadum S.et Z.) on the Cardiovascular System
Abstract:The blood pressure of anesthetized rabbits was significantly decreasedby giving anthraquinone. As a result of accumlation of the drug adminis-tered repeatedly, its lower dose could decrease the blood pressure so sha-rply that the animals would die. Whether the condition is due to hypo-glycemia and/or accumulative toxication should be further studied. The heart rates of the anesthetized rabbits were decreased significantlyby giving anthraquinone, except that any other change was not found inelectrocardiograph.
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