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胆汁反流与食管黏膜上皮损伤的研究进展
引用本文:龚均,张茹.胆汁反流与食管黏膜上皮损伤的研究进展[J].西安交通大学学报(医学版),2007,28(6):605-608.
作者姓名:龚均  张茹
作者单位:西安交通大学医学院第二附属医院消化内科,陕西,西安,710004
基金项目:卫生部临床学科重点项目
摘    要:尽管十二指肠胃食管反流的研究已有100多年历史,但不明点仍很多。本文复习文献并结合我们的研究成果,就胆汁对食管黏膜的损伤,包括损伤的可能机制、食管内胆汁反流的诊断、治疗等方面作以介绍,重点对胆汁在Barrett食管和食管腺癌发生中的作用及其防治作了阐述。

关 键 词:十二指肠胃食管反流  胆盐  食管  上皮细胞  治疗
文章编号:1671-8259(2007)06-0605-04
收稿时间:2007-03-15
修稿时间:2007-09-20

Bile reflux and its' injury on esophageal mucosal epithelial cells
Gong Jun,Zhang Ru.Bile reflux and its'''' injury on esophageal mucosal epithelial cells[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2007,28(6):605-608.
Authors:Gong Jun  Zhang Ru
Abstract:There are also many unanswered questions on the duodenogastroesophageal reflux(DGER),though it has been studied for more than 100 years.Based on the references and our studies,we reviewed the bile' injury on esophageal mucosal epithelial cells,the diagnosis and treatment of bile reflux into esophagus.The relationships of the biles with Barrett's esophagus and esophageal adenocarcinoma were elucidated especially.
Keywords:duodenogastroesophageal reflux  bile salts  esophagus  epithelial cell  therapy
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