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HLA与扩张型心肌病的关联研究
引用本文:张培毅,郭珍,葛克亮.HLA与扩张型心肌病的关联研究[J].西安交通大学学报(医学版),1990(3).
作者姓名:张培毅  郭珍  葛克亮
作者单位:西安医科大学克山病研究室免疫组 (张培毅,郭珍),西安医科大学克山病研究室免疫组(葛克亮)
摘    要:用微量淋巴细胞毒试验检测了20例扩张型心肌病患者的HLA—A、B抗原,并检测了北方汉族无血缘关系的健康人103例作对照。结果发现RR在3以上者有HLA-A28、A31及HLA—B27,但经Fisher确切P值及校正P值处理后,无显著性差异。故未发现与扩张型心肌病有关联的HLA抗原。

关 键 词:人类白细胞抗原  扩张型心肌病  相对危险率

RELATION BETWEEN HLA AND DILATED CARDIOMYOPATHY
Zhang Peiyl,et al.RELATION BETWEEN HLA AND DILATED CARDIOMYOPATHY[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(3).
Authors:Zhang Peiyl  
Institution:Research Laboratory of Keshen Disease
Abstract:This paper reports a study on the relation between HLA and dilated cardiomyopathy. Twenty patients with dilated cardiomyopathy and 103 control subjects of the Han nationality without blood relationship residing in Shaanxi were examined. HLA typing was done by the standard microlymphocytotoxin technique by using 20 cases HLA-A. B. Specificities. we found that RR over three in group of patients with dilated cardiomyopathy was HLA-A28, A31 and HLA-B27. But after dealing with Fisher's P value and correcting P value, no HLA Antigen correlated with dilated cardiomyopathy were detected in this study.
Keywords:Human Ieucocyte antigen  dilated cardiomyopathy  relative risk
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