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土贝母皂甙作为阴道杀精子剂的实验研究
引用本文:苏华,郭仁舆. 土贝母皂甙作为阴道杀精子剂的实验研究[J]. 西安交通大学学报(医学版), 1986, 0(3)
作者姓名:苏华  郭仁舆
作者单位:西安医科大学组织学与胚胎学教研室(苏华),西安医科大学组织学与胚胎学教研室(郭仁舆)
摘    要:本实验证明,土贝母总皂甙及其A、D成分均具有较强的杀精子作用。其瞬间杀精有效浓度分别为0.04%、0.04%及0.03%。其杀精机理主要是破坏精子的生物膜系统。用固定明胶底物薄膜法测定单个精子顶体酶变化的结果表明,三者在浓度为0.05%时均可显著降低单个精子顶体酶的活性。


EXPERIMENTAL STUDIES ON BOLBOSTEMMOSAPONINS USED AS INTRAVAGINAL SPERMATOCIDAL AGENTS
Su Hua Guo Renyu. EXPERIMENTAL STUDIES ON BOLBOSTEMMOSAPONINS USED AS INTRAVAGINAL SPERMATOCIDAL AGENTS[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1986, 0(3)
Authors:Su Hua Guo Renyu
Affiliation:Department of Histo-Embryology
Abstract:This experiment has proved that bolbostemmosaponin and its constituents A and D have relatively powerful spermatocidal effects. They can kill all spermatozoa in a moment at the concentrations of 0.04%, 0.04% and 0.03% respectively. These spermatocidal agents mainly distroy the biomembrane system of sperm. Using the fixed gelatin membrane technique proved that all of them can strongly inhibit tne activity of a single sperm acrosin at the concentration of 0.05%.
Keywords:bolbostemmosaponins  sperm atozoa  spermatocidal agents
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