| GnRH前体分子中的GnRH相关肽在大鼠垂体和睾丸的分布 |
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| 引用本文： | 宋天保,王丽蓉,李乾五.GnRH前体分子中的GnRH相关肽在大鼠垂体和睾丸的分布[J].西安交通大学学报(医学版),1989(4). |
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| 作者姓名： | 宋天保 王丽蓉 李乾五 |
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| 作者单位： | 西安医科大学组织学与胚胎学教研室，西安医科大学组织学与胚胎学教研室，西安医科大学组织学与胚胎学教研室 |
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| 摘 要： | GnRH 相关肽(GAP)是 GnRH 前体蛋白质分子 C-末端56个氨基酸组成的肽。本文应用3种分别抗 GAP N-末端、抗 GAP 中段和抗 GAP C-末端的抗血清,以及免疫组织化学 ABC 法,在大鼠垂体前叶细胞和睾丸间质细胞中染出 GAP 样物质。结果提示 GAP 或其裂解片段对垂体前叶细胞的激素分泌和睾丸间质细胞的功能具有一定的调节作用.
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| 关 键 词： | GnRH相关肽 垂体 睾丸 免疫组织化学 大鼠 |
DISTRIBUTION OF GNRH-ASSOCIATED PEPTIDE OF GNRH PRECURSOR MOLECULE IN RAT PITUITARY AND TESTIS |
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| Song Tianbao,et al.DISTRIBUTION OF GNRH-ASSOCIATED PEPTIDE OF GNRH PRECURSOR MOLECULE IN RAT PITUITARY AND TESTIS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1989(4). |
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| Authors: | Song Tianbao |
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| Institution: | Department of Histology and Embryology |
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| Abstract: | GnRH-associated peptide(GAP)is a 56 amino acid peptide from the C-terminal of the GnRH precursor protein.In this study,GAP like substance wasfound in anterior pituitary cells and Leydig cells of ratsby means of three antisera against N-terminal,mid-region and C-terminal of GAP respectively,andthe ABC immunohistochemical method.The resultssuggest that GAP or its cleavage fragments may havecertain regulating effects on hormone secretion of ante-rior pituitary cells and on function of testicular Leydicell. |
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| Keywords: | GnRH-associated peptide Pituitary Tes(?)is Immunohistochemistry Rat |
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