人体肝片形吸虫感染(附2例报告)

本文报道了2例罕见的人体肝片虫感染。此二例均河南籍,具有发烧、寒战、上腹痛、贫血、肝大、嗜酸性白细胞增高等临床表现,最后以查到虫卵而确诊。其中1例伴有异位寄生,从胸部皮下包块中检获一条肝片虫童虫。2例均经用硫双二氯酚治愈出院。本文结合文献复习,对本病的地理分布、传染途径、病理、预后、诊断、治疗等问题进行了初步讨论。诊断中着重讨论了肝片虫卵与巨片吸虫,姜片虫卵的鉴别要点。

Human Infection with Fasciola Hepatica

Our two patients presented with fever, malaise, anaemia and pains in the upper abdomen. Eosinophilia, increase in serum globulin, decrease in hemoglobulin and tender hepamegala were observed. During the liver biopsy in Casel, many white nodules were seen on the surface of the liver, with small areas of necrosis, indicating eosinophil and lymphocyte infiltration. Ova of F. hepatica were found in the feces and bile of these two patients. The antigen of Fasciolopsis buski skin test was positive and Paragonimus skin test negtive. They were both treated with oral bithionol, which could be considered as an effective form of therapy. The possible source of infection was a wild watercress infected by the encysted metacercaria of Fasciola hepatica when it was eaten raw. The liver fluke, Fasciola hepatica in man, is very rare in the world except a few of counties. In China, about fourteen cases have been reported, including our two cases. The ova of F. hepatica are different from those of F. gigantica in size and from those of Fasciolopsis buski in the yolk granules of the yolk cells of ova. What has been reported above will be useful to clinical medicine.