| AES杀精作用及其对精子超微结构的影响 |
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| 引用本文： | 苗乃周,郭仁舆. AES杀精作用及其对精子超微结构的影响[J]. 西安交通大学学报(医学版), 1991, 0(2) |
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| 作者姓名： | 苗乃周 郭仁舆 |
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| 作者单位： | 延安医学院组织胚胎学教研室(苗乃周)，西安医科大学组织胚胎学教研室(郭仁舆) |
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| 摘 要： | 以脂肪醇聚氧乙烯醚硫酸钠(Fatty Alcohol Polyoxyethylene Ether So-dium Sulfate,AES)作为杀精子剂进行体外实验研究,结果表明,AES具有较强的杀精子效应,它使精子瞬间失活的最低有效浓度为0.08%。透射电镜观察证明,AES损害精子的主要靶结构是细胞膜、顶体和线粒体。
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| 关 键 词： | AES 精子 杀精子剂 表面活性剂 |
SPERMATOCIDAL EFFECTS OF AES ON HUMAN SPERM IN VITRO AND THE ULTRASTRUCTURAL CHANGES OF THE AFFLICTED SPERM |
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| Miao Naichou,Guo Renyu Yanan Medical College Xian Medical University. SPERMATOCIDAL EFFECTS OF AES ON HUMAN SPERM IN VITRO AND THE ULTRASTRUCTURAL CHANGES OF THE AFFLICTED SPERM[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1991, 0(2) |
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| Authors: | Miao Naichou Guo Renyu Yanan Medical College Xian Medical University |
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| Affiliation: | Miao Naichou;Guo Renyu Yanan Medical College Xian Medical University |
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| Abstract: | Fatty Alcohal Polyoxyethylene Ether So-dium Sulfate (AES) was used as aspermatocide to elucidate its spermatocidal ef-fects on human sperm in vitro and theultrastructural changes of the afficted sperm.The results indicate that AES possessesstrong spermatocidal effects and can kill allthe spermatozoa within 1 min at a minimumeffective concentration of 0.08%. TEMobservation shows that the main targetstructures are plasma membrane, acrosomeand mitochondria. |
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| Keywords: | AES spermatozoa spermatocide surfactant |
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