| DISTRIBUTION OF NOS-B1 IN THE MYENTERIC PLEXUS OFRABBIT SMALL BOWELS |
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| 作者姓名： | 吴建维 罗金燕 蒋予 |
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| 作者单位： | Department of Gastroenterology，Second Clinical Medical College，Xi'an Medical University，Xi'an 710004 |
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| 摘 要： | Neuronalnitrcoxidesynthase(NOS)'isknowntoproducenitricoxide(NO)fromL--arginineinthepresenceofreducednicodineamideadeninedinucleotidphosphate(NADPH),calmodulin,andcalciumironstl].RecentpharmacologicalandphysiologicalstudieshaveproposedthatNOplayaroleasaneuronalmessengerofnonadrenergic,non-cholinergic(NANC)relaxationinthegastrointestinaltractinvariousmammalst2.3i.AlthoughneuronalNOShasbeenshowntobeidenticaltoneuronalNADPHdiaphoraseinthebrainoftherate.,.andmostofstudieshavereportedthatt…
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DISTRIBUTION OF NOS-B1 IN THE MYENTERIC PLEXUS OF RABBIT SMALL BOWELS |
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| Wu Jianwei, Luo Jinyan,Jiang Yu.DISTRIBUTION OF NOS-B1 IN THE MYENTERIC PLEXUS OFRABBIT SMALL BOWELS[J].Academic Journal of Xi’an Jiaotong University,1998(1). |
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| Authors: | Wu Jianwei Luo Jinyan Jiang Yu |
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| Abstract: | The distribution or NOS-BI In the myenterlc plexus or the rabbit small ho'vels was studied by using NOS--BI lmm unohlstoc hemlstry with cool emount stal nl ug method. The resul is Indicatedthat the NOS--BI-like lmmunoreactlvity was observed in all specimens or myenterlc plexus. These positive nerve fibers rorlned a regular, ladder-like meSkwork in the myenterlc plexus. The positive product deposited in the cytoplasm, and the majority of NOS-BI neurons had ckaracterlstlcs similar to theDoglel type 1. Thes. cells had many short and long Process. This study provided the morphologicalsupport for the bypotbesls that NO Is pro'duced by neurons and serves as a neurotransmitter in therabbit small bowels. |
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| Keywords: | nitric oxide nitric oxide synthase immunohistochemistry whole mount staining myenteric plexus small bowels rabbit |
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