| USING STR POLYMORPHISM TO STUDY THE GENETIC RELATIONSHIPS AMONG A CHINESE KOREAN POPULATION AND OTHER GROUPS |
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| 引用本文： | 高雅 金天博 李生斌. USING STR POLYMORPHISM TO STUDY THE GENETIC RELATIONSHIPS AMONG A CHINESE KOREAN POPULATION AND OTHER GROUPS[J]. 西安交通大学学报(英文版), 2005, 17(1): 53-56 |
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| 作者姓名： | 高雅 金天博 李生斌 |
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| 作者单位： | State Key Laboratory of Forensic Science，Environment and Genes Related to Diseases Key Laboratory of the Education Ministry，Xi'an Jiaotong University，Xi'an 710061，China，State Key Laboratory of Forensic Science，Environment and Genes Related to Diseases Key Laboratory of the Education Ministry，Xi'an Jiaotong University，Xi'an 710061，China，State Key Laboratory of Forensic Science，Environment and Genes Related to Diseases Key Laboratory of the Education Ministry，Xi'an Jiaotong University，Xi'an 710061，China |
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| 基金项目： | ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina(No.39940401). |
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| 摘 要： | Shorttandemrepeat(STR)polymorphismsare mainlyusedintheforensicfieldforpaternitytests andpersonalidentificationatpresent.Multiplex PCRamplificationandtypingsystemwithmulti coloredfluorescentlabeledprimershavemadeit convenienttogenotypeSTRsusingcommerciall…
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| 关 键 词： | STR 多晶型 朝鲜民族 遗传距离 短衔接重复 |
USING STR POLYMORPHISM TO STUDY THE GENETIC RELATIONSHIPS AMONG A CHINESE KOREAN POPULATION AND OTHER GROUPS |
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| GAO Ya,Jin Tianbo,Li Shengbin. USING STR POLYMORPHISM TO STUDY THE GENETIC RELATIONSHIPS AMONG A CHINESE KOREAN POPULATION AND OTHER GROUPS[J]. Academic Journal of Xi’an Jiaotong University, 2005, 17(1): 53-56 |
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| Authors: | GAO Ya Jin Tianbo Li Shengbin |
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| Affiliation: | State Key Laboratory of Forensic Science, Environment and Genes Related to Diseases Key Laboratory of the Education Ministry, Xi'an Jiaotong University, Xi'an 710061, China |
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| Abstract: | Objective To discuss the genetic relationship between Chaoxian and the other populations with STR polymorphisms, and study the origination of Chaoxian with historical data, analyze the difference among them. Methods Samples were obtained from 91 unrelated individuals of Jilin province. PCR amplification was performed using PE9700, the results were analyzed with the GeneScan software and then using the Genetic Analyzer ABI377 and Genotyper2.5. Tests for Hardy Weinberg equilibrium (HWE) and the clustering map were carried out using SPSS11.5. The DA (genetic distance) according to Nei's was calculated and a phylogenetic tree based on the neighbor-joining method using Mega2 software package was constructed. Results 81 alleles and 196 genotypes were observed, with the corresponding frequencies ranging from 0.0055 to 0.4615 and 0.0110 to 0.2747, the observed and expected of genotypes were evaluated using χ2-test and all of the loci were in accordance with Hardy Weinberg equilibrium (P>0.05). Chaoxian was clustered with the other Chinese ethnic groups, then the American Black and the White; it was clustered with the Baishan Han, the Beijing Han of China first, then the South Korean. Conclusion The differentiation among races is larger than that among minorities, and, the differentiation among minorities is related to and is consistent with their geographic location. |
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| Keywords: | STR polymorphism Korean ethnic group of China(Chaoxian) genetic distance (D A) |
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