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尖锐湿疣患者外周血T细胞亚群的检测
引用本文:张新建,岐天茂,顾晓慧. 尖锐湿疣患者外周血T细胞亚群的检测[J]. 西安交通大学学报(医学版), 1992, 0(4)
作者姓名:张新建  岐天茂  顾晓慧
作者单位:西安市传染病医院,西安医科大学病毒免疫研究室,西安医科大学病毒免疫研究室 710061,西安 710061,西安 710061
摘    要:用T淋巴细胞单克隆抗体和间接免疫荧光技术(IFA)检测尖锐湿疣患者及健康人各20例外周血T淋巴细胞亚群。发现初期患者CD_3阳性细胞百分数显著下降;CD_4,CD_4/CD_8比值也显著下降;CD_8阳性细胞百分数却显著升高;恢复期患者T细胞各亚群比例趋于正常。

关 键 词:尖锐湿疣  T淋巴细胞亚群  间接免疫荧光技术(IFA)

STUDY OF CELL S■BTYPES IN PATIENTS WITH CON■OMA ACUMINATA
Zhang Xinjian,Qi Tianmao,Gu Xiaohui. STUDY OF CELL S■BTYPES IN PATIENTS WITH CON■OMA ACUMINATA[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1992, 0(4)
Authors:Zhang Xinjian  Qi Tianmao  Gu Xiaohui
Affiliation:Department of immunology and virology
Abstract:IFA was used to observe the distribution and the alteration of T-lymphocyte subtypes in the peripheral blood of 20 patiens with condyloma acuminata for 31 times. The murine antibody was the first antient and the antient of rabbit against IGFITC the second. The results showed that the percentage of CD_3 cell in the patients decreased significantly(P<0.01); the percentage of CD_4 cell decreased (P<0.05) and the percentage of CD_8 cell was higher than that of heathy control, therefore, CD_4/CD_8 ratio was obviously low (P<0.01),but after treated with laser and TF,the T-lymphocyte subtype became normal in convalescent stage.
Keywords:condyloma acuminata  T-lymphocyte subtype  IFE  
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