刺激穴位经背根反射引起的神经源性炎症反应

给大鼠静脉注射Ｅｖａｎｓ蓝溶液，切断Ｌ１ 以下所有腹根，保留背根，横断脊髓，同心针电极刺激承山穴３０ｍ ｉｎ，记录并测定皮肤及内脏组织Ｅｖａｎｓ 蓝的含量。结果表明：连续电刺激右侧承山穴，于左、右侧腰部以下皮肤出现似足太阳膀胱经走行的蓝色渗出。测定其Ｅｖａｎｓ蓝含量显著高于旁开１０ｍ ｍ 处（ Ｐ＜ ０．０１），亦显著高于上背部及异体对照组（ Ｐ＜ ０．０１）。同时测定内脏组织的Ｅｖａｎｓ蓝含量发现，膀胱、输尿管及生殖系的含量显著高于异体对照组（ Ｐ＜ ０．０１），穴位刺激经背根反射（Ｄｏｒｓａｌｒｏｏｔ ｒｅｆｌｅｘ，ＤＲＲ）可引起同侧和对侧皮肤及皮下组织跨脊髓节段的似循经走行的神经源性炎症反应，同时可引起同侧和对侧相关内脏组织的神经源性炎症反应

NEUROGENIC INFLAMMATION EVOKED BY STIMULATION OF THE ACUPOINT THROUGH DRR

The purpose of this study is to investigate whether stimulation of the acupoint evoked the neurogenic inflammation distributed along the meridian through DRR (dorsal root reflex).We used 11 rats whose ventral roots below L 1 were cut off and the spinal cords were transected between T 13 and L 1.After intravenous injection of Evans blue liquid and continuous electrostimulation of the right Chengshan acupoint of the rat,Evans blue extravasation distributed along the Bladder Meridian of Foot Taiyang was observed on the skin of lower back and both hindlimbs.By means of measuring the amount of Evans blue, it was shown that the amount of Evans blue spot in the skin with the extravasation was obviously different from that in the skin of 1.0mm apart from (P<0.01),also obviously different from that in the skin of the upper back and from that in the skin of the control group (P<0.01),also shown that the amount of Evans blue in the bladder, ureter and germen was obviously different from that in the control group (P<0.01).These results indicate that the stimulation of the acupoint may produce the neurogenic inflammation of ipsilateral and contralateral skin up to several adjacent spinal segments as well as may produce the neurogenic inflammation of ipsilateral and contralateral visceral organs related to the Bladder Meridian through DRRs.