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脑肿瘤患者手术前后免疫功能的观察
引用本文:郭世文,刘守勋,谢昌厚,马列婷. 脑肿瘤患者手术前后免疫功能的观察[J]. 西安交通大学学报(医学版), 1996, 0(1)
作者姓名:郭世文  刘守勋  谢昌厚  马列婷
作者单位:西安第一附属医院神经外科
摘    要:对27例脑肿瘤患者手术前后免疫功能进行了检测。结果血清IgG、IgA和IgM的改变与正常组相比,手术前后均无明显差异(P>0.05);淋巴细胞亚群较正常组降低极为明显(P<0.001),肿瘤切除术后细胞免疫功能有所恢复,但与术前比较无明显差异(P>0.05),且仍显著低于正常状态(P<0.01)。说明脑肿瘤病人体液免疫无变化,细胞免疫功能则明显低下,且肿瘤切除术后其细胞免疫功能尚难很快恢复到正常状态。

关 键 词:脑肿瘤,手术,免疫球蛋白,细胞免疫

OBSERVATIONOF IMMUNE RESPONSE TO THE PATIENTS WITH BRAIN TUMORS IN PRE-AND POST-OPERATION
Guo Shiwen, Liu Shouxun,Xie Changhou,et al. OBSERVATIONOF IMMUNE RESPONSE TO THE PATIENTS WITH BRAIN TUMORS IN PRE-AND POST-OPERATION[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1996, 0(1)
Authors:Guo Shiwen   Liu Shouxun  Xie Changhou  et al
Abstract:The immune status of27 patients with brain tumors was measured by pre-and postoperative immunoglobulins and Tcell subset respectively.The result showed that pre-and post-operative serum immunoglobulin-IgG,IgA and IgM were not significantly different(P>0.05).Tcell subset was much lower in patients than in control subjects group (P< 0.001).The cell inediated immunity increased slightly after tumor removal.But there was no significantdifferencebetween thepreandpost-operation(P>0.05),and the cellular immunity was significantly lower in post-operation than in normal status(P<0. 01).From the above dataitisindicatedthatthehumoralimmunity was not changed,the cellular immunity decreased much in the patients with brain-tumor, and it is difficult for the cellular immunity to recover in short-time after tumor removal
Keywords:brain tumor  operation  cellular immunity  immunoglobulin
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