甲、乙型肝炎病毒重复感染的血清学检测

本文分析60例甲、乙型肝炎病毒重复感染的血清学检测结果,提示重复感染占当时住院肝炎病人的14.8%。在重复感染中,同时感染甲、乙两型肝炎者9例;乙肝抗原携带者及慢性肝炎基础上感染甲肝者41例;乙肝隐性感染免疫后又感染甲肝者10例.同时观察到部分病人重复感染时,HBsAg 滴度下降或消失。并探讨了肝炎复发或突然加重的原因,认为两种肝炎病毒重复感染是肝炎复发或者突然加重的主要因素.故预防HBV 携带者及慢性乙肝重复感染其他肝炎病毒十分重要.

A SEROLOGICAL STUDY OF HEPATITIS A VIRUS AND HEPATITIS B VIRUS SUPERINFECTION

Sixty patients with hepatitis A virus(HAV)andhepatitis B virus(HBV)superinfection were studiedserologically.It was found that these patients made up14.8% of the total hepatitis inpatients during theperoid of study.Among these 60 patients.9 cases wereinfected with HAV and HBV simultaneously.41 caseswere infected with HAV on the basis of chronic HBVinfections(asymptomat(?)c HBsAg carriership or chronichepatitis B),and the other 10 cases were infected withHAV when immunity against HBV had been developeddue to previous subclinical infections with this virus.Itwas also found in some as cases that the titre ofHBsAg declined or disappeared when superinfectionoccurred.Superinfection with two types of hepatitis vi-ruses may be a signifecant cause of relapse or aggrava-tion of hepatitis.Thus,it is of great importance to pre-vent both asymptomatic HBsAg carriers and chronichepatitis B patients fron being infected with other typesof hepatitis viruses.