| 环磷酰胺早期治疗流行性出血热的疗效观察 |
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| 引用本文： | 谢蔚玫,张成文. 环磷酰胺早期治疗流行性出血热的疗效观察[J]. 西安交通大学学报(医学版), 1983, 0(2) |
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| 作者姓名： | 谢蔚玫 张成文 |
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| 作者单位： | 西安医学院附属一院传染病教研室，西安医学院附属一院传染病教研室 |
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| 摘 要： | <正> 七十年代以来,国内外的研究提示流行性出血热的发病机理与免疫反应有关,并证实体内有免疫复合物的存在。为了抑制免疫反应,减少免疫复合物的形成,从而减轻病理损害,降低病死率。我们对收治的部分流行性出血热早期患者采用了免疫抑制剂——环磷酰胺及细胞免疫增强剂——植物血凝素(PHA)进行了治疗观察,结果如下:
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Observation on the Therapeutic Effect of Cytoxan in the Treatment of Early Epidemic Hemorrhagic Fever(EHF) |
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| Abstract: | During the year of 1981, 60 patients admitted with EHF within 5 days after onset were equally divided into a cytox-PHA-treated group and a control group at random, and the results were compared. The clinical conditions were similar in the two groups. Different from part of those reported previously in our country, our data showed that the therapeutic results were worse in the cytox-PHA-treated group than in the control group. Thus, we suggest that the effect of immuno-moderating agents on EHF needs further study. |
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