| 乙型肝炎病毒(HBV)感染者粪便中HBsAg检出情况及其传染性研究 |
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| 引用本文： | 徐慧文,徐经武,王学良,门伯媛,杨少毅.乙型肝炎病毒(HBV)感染者粪便中HBsAg检出情况及其传染性研究[J].西安交通大学学报(医学版),1988(4). |
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| 作者姓名： | 徐慧文 徐经武 王学良 门伯媛 杨少毅 |
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| 作者单位： | 西安医科大学流行病学教研室
(徐慧文，徐经武，王学良，门伯媛)，西安医科大学电子显微镜室(杨少毅) |
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| 基金项目： | 1987年国家自然科学基金 |
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| 摘 要： | 对25名HBV新感染者和11名无症状携带者粪便中HBV感染性指标进行了观察,在所研究的36人中,72.2%可检出HBsAg,如按检测份数计算, 阳性率为35.2%(57/162)。在HBsAg阳性粪便中24.7%(23/93)可以检出HBeAg.并有2份标本HBV—DNA阳性。由于应用了超速离心技术和单克隆抗-HB_s,电镜下多数标本可见抗原颗粒呈大片聚集,其大小、形态与HBsAg阳性血清中所见无异。
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| 关 键 词： | HBV感染者 HBsAg 无症状携带者 |
STUDY ON HBsAg DETECTION IN FEACES OF INFECTED PERSONS WITH HBV INFECTION AND ITS INFECTIVITY |
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| Xu Huiwen,et al.STUDY ON HBsAg DETECTION IN FEACES OF INFECTED PERSONS WITH HBV INFECTION AND ITS INFECTIVITY[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1988(4). |
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| Authors: | Xu Huiwen |
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| Institution: | Department of Epidemiology |
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| Abstract: | HBV infection markers were oberved in the feaces of 25 newly-infected persons and 11 asymptomatic carriers, In all the 36 subjects, HBsAg was detected, with a detectable rate of 72.2%; according to the number of feaces samples, the positive rate of HBsAg was 35.2%(57/162). Of the samples of those who had HBsAg detected, the positive rate of HBeAg was 24.7%(23/93), and HBV-DNA was positive in 2 of 51 HBsAg positive samples. With immunoelectromicroscope round particles of larger clustering HBsAg were found in most of feaces samples; bacause of the use of ultracentrifugal method and monoclonal anti-HBs, their shape and size were the same as those found in HBsAg positive serum. |
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| Keywords: | asymptomatic carriers HBsAg HBV infcction marker |
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