尸体肾移植术后加速性排斥反应的临床治疗体会

目的 探讨尸体肾移植术后加速性排斥反应的临床治疗。方法 对7例临床上诊断为加速性排斥反应的患者给予强有力的抗排斥治疗。结果 自1996年5月至1999年5月所行的300例尸体肾移植患者中，7例发生加速性排斥反应，发生率2..33%，经强有力的抗排斥治疗后6例完全逆转，排斥逆转率85..5%，目前6例均健康存活，带肾存活率最长已达3年半；1例治疗无效切除移植肾。结论 加速性排斥反应的防治重点在于早期诊断、及时强有力的抗排斥治疗以及有针对性地防治抗排斥治疗过程中可能出现的各种并发症。

Clinical experience of treating accelerated rejection of cadaver renal transplantation

Objective\ To discuss the way of treating accelerated r ejection.Methods\ Seven patients of accelerated rejection were t reated by efficient antirejection treatment. Results\ Six patients of accelerated rejection were reversed by effi cient treatment of antirejection.One allograft was removed because treatment w as invalid.And six patients were still alive,the longest survival one has reache d to 3 years.Conclusion\ The treatment emphasis of accelerated rejec tion should be focused on 3 aspects,including early diagnosis,efficient treatmen t in time,and paying more attention to any possible complications during the pro cess of treatment.