| THE CELL ORIGIN OF INTERLEUKIN 6 IN THE DISEASE OF MULTIPLE MYELOMA |
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| 作者姓名： | 鲍德虎 张亮轩 董晓慧 |
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| 作者单位： | Department of Microbiology，Xi'an Medical University，Xi'an 710061 |
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| 摘 要： | ＴＨＥＣＥＬＬＯＲＩＧＩＮＯＦＩＮＴＥＲＬＥＵＫＩＮ６ＩＮＴＨＥＤＩＳＥＡＳＥＯＦ ＭＵＬＴＩＰＬＥ ＭＹＥＬＯＭＡＢａｏＤｅｈｕ；ＺｈａｎｇＬｉａｎｇｘｕａｎ；ＤｏｎｇＸｉａｏｈｕｉ；（ＤｅｐａｒｔｍｅｎｔｏｆＭｉｃｒｏｂｉｏｌｏｇｙ，Ｘｉ＇ａｎＭ...
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THE CELL ORIGIN OF INTERLEUKIN 6 IN THE DISEASE OF MULTIPLE MYELOMA |
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| Bao Dehu,Zhang Liangxuan,Dong Xiaohui,.THE CELL ORIGIN OF INTERLEUKIN 6 IN THE DISEASE OF MULTIPLE MYELOMA[J].Academic Journal of Xi’an Jiaotong University,1996(2). |
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| Authors: | Bao Dehu Zhang Liangxuan Dong Xiaohui |
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| Abstract: | In order to investigate the cell origin of IL-6 in the disease of multiple myeloma(MM),the IL-6 levels in PBMC culture supernatants from MM and the healthy control were determined with 7TD1 hybridoma growth assay and the ability or MM cell and stroma cell to produce IL-6 was compared.The results showed IL-6 level in PBMC culture supernatants of MM group was evidently higher than that of the control group.Both MM cell and stroma cell could produce IL-6, but IL-6 amount produced by MM cell was 1.6 times as much as that by stroma cell(P<0.01).The results suggest that MM cell is the main cell to produce IL-6. |
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| Keywords: | multiple myeloma interleukin-6 autocrine paracrin |
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