外周神经末梢相互影响的研究——循经感传外周机制的探讨

1977年作者曾提出经络实质二重反射假说。认为针刺除通过中枢引起反射效应外(长反射),还可能通过外周神经末梢的联系传递信息(短反射)。本实验用大鼠,以氨基甲酸乙脂麻醉,找出并切断腓浅与腓深神经,断绝其与中枢的联系。电刺激腓浅神经而在腓深神经干与引导动作电位(AP)。结果发现只有少数可以引出(5.7%),但在“足三里”穴电针诱导30分钟,拔出毫针后,再用电刺激腓浅神经,在29只大鼠中有17只(58.6%)从腓深神经干上引出了AP。由于“足三里”的部分组织既有腓浅又有腓深神经支配,故本实验提示在一定条件下外周神经末梢间能够进行信息传递,一根神经纤维的冲动可以通过末梢引起另一纤维的兴奋。这种信息传递也许是经络感传的实质。

A STUDY OF THE INTERACTION BETWEEN PERIPHERAL NERVES——RESEARCH ON MECHANISM OF PROPAGATED SENSATION ALONG THE CHANNELS

With regard to the nature of meridians, the authors have presented the hypothesis of dual reflex in 1977. This means that acupunture can invoke some effects not only through CNS (long reflex), but through the connection of peripheral nerve terminals to transmit messages (short reflex). In this experiment, rats were anaesthetized by rethane. The superficial peroneal nerve (SPN) and the deep peroneal nerve (DPN) were found out and cut off in order to break off their connection to CNS. With electrical stimulation of SPN, the action potential (AP) on the DPN was recorded at the same time. AP was induced only in a few cases (5.7%). But, after electroacupuncture was reapplied to Zusanli (ST-39) point for 30 rain, we stimulated SPN with electricity. This showed that APs were recorded on DPN in 17 among 27 rats (58.6%). Since some tissues around Zusanli point involve both SPN and DPN, the results suggest that messages are transmitted between nerve terminals under certain condition and that impluses on a nerve stem may stimulate another nerve terminal. This might be the essence of propagated sensation along the channels.