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乙型肝炎肝细胞特异性抗体的检测—肝细胞—SPA花结形成试验
引用本文:史尔丽,张树林,李义方.乙型肝炎肝细胞特异性抗体的检测—肝细胞—SPA花结形成试验[J].西安交通大学学报(医学版),1984(3).
作者姓名:史尔丽  张树林  李义方
作者单位:西安医学院第一附属医院传染病学教研室,西安医学院第一附属医院传染病学教研室,西安医学院第一附属医院传染病学教研室
摘    要:本文报告我们建立的肝细胞—葡萄球菌A蛋白花结形成试验(L—SPA—R),检测各型乙肝患者血清中肝细胞特异性抗体73例的结果。表明重肝与慢活肝患者L—SPA—R形成率高于慢迁肝(P<0.001),急肝患者急性期显著高于恢(?)期(P<0.001),L—SPA—R持续升高可能慢性化。说明自身免疫反应在乙肝,特别是在慢活肝发病机理中起一定作用。

关 键 词:抗体  乙型肝炎

Determination of Liver Specific Antibodies in Viral Hepatitis B with a New Method for Liver Cell—SPA—Rose Forming Test
Shi Erli et al.Determination of Liver Specific Antibodies in Viral Hepatitis B with a New Method for Liver Cell—SPA—Rose Forming Test[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1984(3).
Authors:Shi Erli
Institution:Shi Erli et al Department of Infections Diseases,First Affiliated Hospital,Xi'an Medical College)
Abstract:This paper reports a new method established in our laboratory, called a liver cell-SPA-rose (L-SPA-R)forming test which was used to determine liver specific antibodies in viral hepatitis B in the study group(73 cases) and the control group (20 cases). The results showed that the L—SPA—R forming rate is higher in severe hepatitis and chronic active hepatitis than in chronic persistent hepatis(P<0.001), and it is also higher in the acute stage of acute hepatitis than in the convalescent stage. When the L-SPA-R forming rate increases continuously, acute hepatitis may become chronic, indicating that autoimmunization reaction plays an important role in hepatitis B, especially in chronic active hepatitis. The experimental method and its mechanisms are described briefly.
Keywords:Antibodies  Hepatitis B
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