肺间质性病变中肺血管损害的MRI表现和病理对照观察

通过肺间质性病变的动物模型，对肺血管损害的情况进行了MRI和病理学的对照研究。发现在肺间质病变中，MRI表现为T1WI肺血管走行僵直，边缘模糊不清，呈中等稍低的信号阴影。T2WI肺血管周围有边缘不清、模糊的中等偏高信号阴影。其病理学主要表现为肺血管壁结构疏松、水肿，有少许纤维组织增生。肺血管周围的肺间质充血、水肿。肺泡内充满了浆液性渗出，炎细胞浸润。作者认为MRI检查对于相对早期的肺间质性病变中，有关肺血管损害或肺实质损害的观察，不失为一种可行的方法。

MRI AND PATHOLOGIC COMPARATIVE OBSERVATION OF PULMONARY VESSELS IN PULMONARY INTERSTITIAL DISEASE

MAI and Pathologic comparativestudy of pulmonary vessesls was pressnted on animal model of pulmonary interstitial disease. Therigid distribution and hazy edge of pulmonay vessels, which was slightly lower signal density, couldbe seen on T1 WI. The area around pulmonary vessels were nuclear and hazy, which showed slightlyhigh signal density on T2 WI. On pathologic study,the structue of wall of pulmonary vessels were rarefactive, edema and slight fibrosis. There were congestion, edema of pulmonary interstitial around vessels. There were serious exudation and cellular infiltration in alveoli. So we think it is a possible way touse MRI in examination and observation for the early lung interstitial disease, lung vessel damage andlung parenchyma damage.