| 小儿T淋巴细胞亚群的正常值的探讨 |
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| 引用本文： | 陈明钰,孙晓春.小儿T淋巴细胞亚群的正常值的探讨[J].西安交通大学学报(医学版),1991(1). |
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| 作者姓名： | 陈明钰 孙晓春 |
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| 作者单位： | 第四军医大学唐都医院小儿科，第四军医大学唐都医院小儿科 西安医科大学卫生系微生物学及免疫学教研室 |
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| 摘 要： | 本文采用抗人T淋巴细胞单克隆抗体免疫荧光技术,对35例健康小儿的T细胞亚群进行了初步探讨。检验结果7岁～11岁健康小儿的CD_366～70%,CD_436～40%,CD_827～32%,CD_4/CD_8 0.86～1.76。本组资料的测定值与武汉、上海的类似研究进行了初步比较,对有关T细胞亚群的临床应用情况进行了初步讨论。鉴于健康小儿的T细胞亚群值报道甚少,建议本组测定值可作为类似研究时之参考值。
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| 关 键 词： | T淋巴细胞亚群 抗人T细胞单克隆抗体 间接免疫荧光技术 |
INVESTIGATION OF T LYMPHOCYTE SUBSET IN HEALTHY CHILDREN |
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| Chen Mingyu,Sun Xiaochun.INVESTIGATION OF T LYMPHOCYTE SUBSET IN HEALTHY CHILDREN[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1991(1). |
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| Authors: | Chen Mingyu Sun Xiaochun |
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| Institution: | Chen Mingyu,Sun Xiaochun Department of Pediatrics,The Second Hospital,The Fourth Military Medical College |
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| Abstract: | The peripheral blood T lymphocyte subsets can be ob-served by monoclonal antibodes Monoclonal antibodesindirect immunoflurescert techrique was used in ourstudies The lymphocytes subsets in children rangingfrom 7～11 years was not significantly different Aftertaking statistical analysis by t-test, we found the nor-mal values in both sexes on each age was notsignificantly differnet The normal values of Tlymphocyte subsets in 35 healthy children were CD_366～70%,CD_4 36～40% CD_8 27～32%,CD_4/CD_8 0.86～1.76 The bove mentioned resultssuggested the normal values of T lymphocytes subsetscan be used as references in children over 7 years.There has been few reports on the T Lymphocytesubsets in healthy children in our country, but it is con-siderably valuable. It is related to the pathogenic mecha-nism of sever 1 diasese, more specifically, immunologicdisorders of children |
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| Keywords: | T lymphocytes subsets T lymphocyte monoclonal antibodies indirect immunoflurescence techniqu |
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