SS4B电力机车转向架可视化标准作业系统研究

SS_4B型电力机车转向架结构复杂,检修工序繁琐,对作业人员的检修技能培训要求高,针对目前培训方式存在的问题,提出建立转向架可视化标准作业系统,综合利用多媒体技术、数字化建模技术以及虚拟现实技术,构建集三维动画和人机交互功能于一体,信息集中化、培训作业标准化、培训时空自由化、周期短且考核针对性强的可视化培训系统,实现对SS_4B型电力机车转向架系统的内部结构、检修流程及其动态拆装过程的逼真模拟,提升实操培训效率和沉浸式体验,提高检修人员技能水平。     

轨道复合不平顺对无缝线路横向变形的影响分析

轨道复合不平顺会对行车的安全及稳定性产生较大影响,也是影响无缝线路横向变形的一个重要因素。为研究轨道复合不平顺对无缝线路的具体影响,通过构建三维轨道框架非线性有限元模型,采用轨道框架单点(或多点)位置发生横向及竖向位移来模拟复合不平顺状态,通过计算获取节点位移变化规律,进而分析轨道复合不平顺对无缝线路横向变形的影响作用。研究结果表明,轨道的复合不平顺会对无缝线路的横向变形产生显著的影响;当线路出现三角坑等类似病害时,其节点位移变化更为显著,在无缝线路的日常养护维修中应尤为注意。     

Environmental and transport effects of warehouse relocationing: evidence from Norway

Reducing traffic volumes and CO2-emissions from freight transport has proven difficult in many countries. Although the increasing suburbanization of warehouses is seen as a relevant land use trend, comprehensive analyses of their impact remain scarce. This study uses real data in modeling transport, costs, environmental and modal effects from warehouse relocations around Oslo and Trondheim (Norway). Results indicate that for Oslo, traffic performance (ton-km), CO2-emissions, and transport costs increase following warehouse suburbanization. For Trondheim, transport performance and CO2-emissions increase less, while transport costs decrease marginally. We conclude that specific case characteristics (geography and trade patterns) are important in determining the strength and direction of effects, and expect that common concomitant developments (warehouse centralization and consolidation) would lead to more pronounced results. Our findings confirm some, but challenge other, findings from the relatively scarcely literature available. Finally, the study's more general insights and observations can help advance similar analyses beyond Norway.     

Data dependent input control for origin–destination demand estimation using observability analysis

In this paper, we address the observability issue of static O–D estimation based on link counts. Unlike most classic observability analyses that relied only on network topological relationships, our analysis incorporates the actual values of input parameters, thus including network operational relations as well. We first analyze possible mathematical properties of an O–D estimation problem with different data input. We then propose a modeling approach based on mixed-integer program for selecting model input that ensures observability and estimation quality. Through establishing a stronger connection between observability analysis and the corresponding estimation problem, the proposed method aims to improve estimation quality while reducing reliance on erroneous data.     

基于多源数据的公交车能耗碳排放测算模型

公交车能耗碳排放强度与车辆、线路和驾驶员有显著相关关系，为精准刻画其能耗碳排放强度特征，整合OBD监测数据、加油(气)数据、运营排班数据等多源数据资源. OBD监测数据和加油(气)数据呈显著的线性关系，证明修正后的OBD监测数据可满足分析要求. 搭建“速度-能耗碳排放强度曲线”测算模型，幂函数关系的拟合优度R2 =0.972 6 为最高. 实证研究发现，平均速度在10~60 km/h 变化时，液化天然气(LNG)车比柴油车能耗碳排放强度高 3.3%~33.7%，双层车比铰接车高2.4%~13.3%；LNG铰接车在不同线路、相同速度下的强度相差9.6%；不同驾驶员在相同线路的能耗碳排放强度可相差24.2%. 模型为各城市基于多源数据开展公交能耗碳排放目标设定提供数据支撑.     

Validating and improving public transport origin–destination estimation algorithm using smart card fare data

Smart card data are increasingly used for transit network planning, passengers’ behaviour analysis and network demand forecasting. Public transport origin–destination (O–D) estimation is a significant product of processing smart card data. In recent years, various O–D estimation methods using the trip-chaining approach have attracted much attention from both researchers and practitioners. However, the validity of these estimation methods has not been extensively investigated. This is mainly because these datasets usually lack data about passengers’ alighting, as passengers are often required to tap their smart cards only when boarding a public transport service. Thus, this paper has two main objectives. First, the paper reports on the implementation and validation of the existing O–D estimation method using the unique smart card dataset of the South-East Queensland public transport network which includes data on both boarding stops and alighting stops. Second, the paper improves the O–D estimation algorithm and empirically examines these improvements, relying on this unique dataset. The evaluation of the last destination assumption of the trip-chaining method shows a significant negative impact on the matching results of the differences between actual boarding/alighting times and the public transport schedules. The proposed changes to the algorithm improve the average distance between the actual and estimated alighting stops, as this distance is reduced from 806 m using the original algorithm to 530 m after applying the suggested improvements.     

浅埋顶管沉井周边土体的三维破坏形状及沉降研究

为研究顶管沉井及周边土体在顶进力作用下的形变范围与大小，以加固旋喷桩作为沉井周围加固体建立ABAQUS软件计算模型，并将模拟结果与工程实例、PLAXIS 3D软件所得结果进行对比分析。同时，采用广州地区花岗岩残积土进行室内沉井模型试验，并通过试验结果对数值模拟结论进行验证，得出结论如下： 1）在开挖基坑前达到设计强度的旋喷桩能有效减小基坑周边土体塌陷变形、坑底隆起。2）在施加工作顶推力下，前侧主动区首先出现贯通裂缝，竖向位移斜率增大出现明显拐点；继续增大顶推力，土体位移会急剧增大导致地表沉降严重。3）对于后背土体，在顶推力作用下，地表破裂线的切线角度从0°逐渐增大至45°+φ/2，导致破裂范围也不断扩大；达到45°+φ/2处后，继续施加顶推力会导致短轴方向破坏范围扩大的速度较长轴方向的速度更快；三维空间中被动区破坏土体在地表处产生形状为椭圆的破坏面，椭圆长轴方向为顶推轴线方向，被动破坏体呈现为牛角状椭圆楔体。     

羟基喜树碱对人胆管癌QBC939裸鼠移植瘤PS2、COX-2的影响

目的探讨羟基喜树碱对人胆管癌QBC939裸鼠移植瘤的乳癌相关肽(PS2)、环氧合酶-2(COX-2)的影响,分析PS2、COX-2与肿瘤发生、发展的关系。方法建立人胆管癌QBC939细胞株裸鼠皮下移植瘤模型,将30只裸鼠随机分成对照组、羟基喜树碱低剂量组和羟基喜树碱高剂量组,观察移植瘤体生长情况,RT-PCR法检测瘤体内PS2、COX-2 mRNA表达。结果与对照组比,羟基喜树碱低、高剂量组都可使移植瘤体的PS2 mRNA表达增高;COX-2 mRNA表达降低,且瘤体生长减慢,与对照组比较差异有统计学意义(P<0.01)。结论羟基喜树碱可降低移植瘤COX-2 mRNA表达,增高移植瘤体的PS2 mRNA表达,并使人胆管癌裸鼠移植瘤生长减慢。     

Study on T lymphocyte subsets and NK cells in patients with Graves＇ disease combined with type 2 diabetes

Objective To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD)and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods Fifteen cases of GD/ T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.