~(60)Co射线放疗前后癌症患者外周血淋巴细胞染色体畸变频率

本文以50例正常人为对照组与50例食道癌、宫颈癌患者和30例经~(60)Co射线放疗的癌症患者外周血淋巴细胞的染色体畸变率(CAs)进行了比较研究。发现放疗前患者的CAs比正常人明显升高,而放疗后的患者,CAs又明显高于放疗前的患者,这些都说明了CAs不仅可作为癌症患者的细胞遗传标记物,而且也能检测由~(60)Co射线所诱导的遗传学效应。肿瘤的发生和射线的局部照射同样影响了患者的外周血淋巴细胞。     

夫妻配对MTHFR基因型分布与不明原因反复流产的关系

目的　探讨亚甲基四氢叶酸还原酶 (MTHFR)基因多态性在夫妻间的不同存在形式与不明原因反复流产之间的关系。方法　采用聚合酶链反应 限制性片段长度多态性 (PCR RFPL)的方法 ,对 32对有两次及两次以上不明原因流产史的夫妇和 39对健康夫妇进行MTHFR6 77C→T突变相关性研究。结果　病例组与正常对照组流产发生的危险性比较 ,夫妻双方都是纯合或杂合突变型 ,其基因型分布与流产发生的危险性增高高度相关 ,OR =2 94 1,95 %CI[1.0 6 2～ 8.133];夫妻双方有一人是纯合或杂合突变型 ,而另一人为野生型的 ,其基因型分布与流产发生的危险性无关联 ,OR =0 .819,95 %CI[0 .32 0～ 2 .0 94 ];夫妻双方都是野生型 ,其基因型分布与发生流产的危险性降低高度相关 ,OR =0 188,95 %CI[0 .0 4 6～ 0 .76 0 ]。结论　子代携带MTHFR纯合或杂合突变可能是胚胎早期发育异常的原因之一 ,从而导致流产的发生。     

DISCRETE VARIABLE STRUCTURE CONTROL OF LINEAR TIME-INVARIANT SYSTEMS WITH TIME DELAY

IntroductionIn recentyears,many methods have been pro-posed for the design of time- delay control sys-tems[1,2 ] and criteria for the stability of time- delaysystems have been developed by many re-searchers[3 ,4] .Time delay in the control systemscan be divided into two classes on the whole.Oneis in measurement of system variables and calcula-tion for required control force,including physicalproperties of equipmentused in the systems or sig-nal transmission.The other is in control for actua-to…     

An Innovative On-Board Computer for Space Robot

In this paper an on-board computer system for the first Chinese Intelligent Space Robotic System was presented. A fault tolerance design on on-board computer （OBC） was proposed that allows commercial-off-the-shelf （COTS） devices to be incorporated into dual processing modules of on-board computer. The processing module is composed of 32-bit ARM RISC processor and other COTS devices. This innovative approach deeply relies on light weight/low cost equipment development using commercial miniaturized parts and non-space qualified technologies. As well as, a set of fault handling mechanisms was implemented in the computer system. The on-board software was organized around a set of processes that communicate between each other through a routing process. The qualification experiment shows that the fault tolerant on-board computer has excellent data processing capability and is enough to meet the demanding of the extremely tight constraints on mass, volume, power consumption and space environmental conditions.     

成人界嵴形态与组织结构的观察

目的　观察和测量人右心房界嵴和梳状肌的形态和组织结构 ,以探讨其可能的功能。方法　肉眼观察、测量界嵴与梳状肌的有关形态学数据。利用光学显微镜 ,通过HE、Masson和磷钨酸 苏木素染色 ,对界嵴的细胞形态和纤维方向等进行细致观察。结果　①根据界嵴的隆起状况 ,界嵴可分为 4类 :A .全程隆起 (18.6 % ) ;B .上 2 / 3隆起 ,下1/ 3平坦 (2 7.9% ) ;C .上 1/ 3隆起 ,下 2 / 3平坦 (34.88% ) ;D .全程平坦 (18.6 % )。②界嵴的肌纤维可分深、浅两层 ,深层肌纤维纵行 ,与界嵴长轴平行 ;浅层纤维横行 ,仅见于界嵴的中、下部 ,深 浅层纤维之间互相联系。在界嵴各处可见P样细胞。③根据梳状肌的起止和走行 ,梳状肌可分为 3型 :汇聚型、网状型和混合型。结论　窦房结上、下及其深面借过渡纤维与界嵴的普通肌纤维相互联系 ,界嵴纤维可能与结间冲动传导有关。梳状肌走行方向的多样性 ,可能与临床上心脏电流传导的多向异性有关     

中药内异消对大鼠子宫内膜异位症血管生成因子的影响

目的　探讨血管内皮生长因子 (VEGF)、肿瘤坏死因子 (TNF α )在子宫内膜异位症 (EM)发病机制中的作用及相互关系 ,观察中药内异消对两因子的影响及对EM的治疗作用。方法　采用种植内膜方法建立EM动物模型 ,内异消治疗 ,丹哪唑对照 ,ELISA法测定TNF α水平 ,免疫组化SP法检测VEGF表达。结果　EM病模组异位内膜组织中VEGF的表达及腹腔液TNF α含量显著增高 ,与假模型组比较有统计学差异 (P <0 .0 1) ;内异消能降低VEGF表达及TNF α含量 ,与病模组比较有统计学差异 (P <0 .0 1)。结论　VEGF、TNF α在EM发生发展中起重要作用 ,内异消可通过调节两因子的表达来抑制异位内膜的生长     

REPORT OF HLA DISTRIBUTION IN 2315 VOLUNTEER DONORS OF CHINESE BONE MARROW BANK FROM NORTHWEST CHINA

HumanLeukocyteAntigen(HLA)system, knownashumanmajorhistocompatibilitycomplex (MHC),playsakeyroleinantigenprocessing,im muneregulationandotheraspects.HLAisalsobeen calledastransplantingantigenasaccuratetypingof HLAonbothpatientanddonorcanincreasedramat i…     

Investigation of Wall Pressure Fluctuations in a Turbulent Boundary Layer by Large Eddy Simulation

Large eddy simulation (LES) was used to investigate the space-time field of the low Mach number, fully developed turbulent boundary layer on a smooth, rigid flat plate. The wall-pressure field simulated by LES was analyzed to obtain the pressure statistics, including the wall-pressure root-mean square, skewness and flatness factors, which show the wall pressure distribution was not Gaussian. The profile of the auto-power spectral density and the contour of the streamwise wavenumber-frequency spectral density of wall-pressure were plotted. The "convection ridge" can be observed clearly and the convection velocity can be calculated from the location of the convection peak.     

Study on Distributed Motion of Self-Reconfigurable Robot Based on Local Rules

The eigenvector of a module with six adjacent module's state was constructed according to self-reconfigurable robot M-Cubes and the configuration of system was expressed with the eigenvectors of all modules.According to the configuration and motion characteristics of the modules,a 3-dimension motion rule set was provided.The rule sets of each module was run according to eigenvector of the module after the motion direction of system decided and motion rules were selected.At last,the rapid and effective motion and metamorphosis were realized in system.The rule sets are operated on three systems and the distributed motion of system is fully realized.The result of simulation shows that the 3-dimension motion rule sets has perfect applicability and extensibility.The motion steps and communication load of the modules increase with the module number in linear.     

微型扑翼飞行器空气动力学研究进展

微型扑翼飞行器(FMAV)作为一种新概念的航空器,有着广泛的功能和用途,已经受到了各国的高度重视.综述了国内外对微型扑翼飞行器的低雷诺数空气动力学问题的研究现状及未来的发展趋势,讨论了目前研究中需要解决的一些关键技术.在此基础上,总结出今后研究的重点,并为微型扑翼飞行器的设计提供了参考依据.