上海帕萨特轿车为何无法启动?

一辆上海大众帕萨特1.8T轿车因无法启动需救援抢修。根据车主描述,得知该车早上发车时突然出现无法启动的故障,在此之前车辆运转一直正常。汽车启动时,电瓶、启动机均正常,发动机启动也没有任何异响,但是发动机没有着车迹象。     

株洲湘江四桥部分斜拉桥设计

株洲湘江四桥主桥采用75m＋2×140m＋75m三塔单索面预应力砼部分斜拉桥。文中着重介绍该桥主梁、索塔、拉索的设计与结构的整体计算。     

碎石桩地基综合检测分析

青藏铁路DK1909＋024涵洞地基处理采用碎石桩复合基础．该场地位于基坑内，场地内地下水埋深较浅．为了查明碎石桩复合地基承载力的改善情况，采用重型动力触探试验、桩间土钻探、静载试验、试坑检测四种方法，得出了相应的结果分析，对该涵基作出了综合评价．     

糖尿病与胰腺癌关系的探讨

目的 探讨糖尿病与胰腺癌的关系,高血糖对胰腺癌组织内神经的影响.方法 采用病例对照研究对我院1999年1月至2008年3月诊治的胰腺癌患者513例进行回顾性研究,分为血糖升高组和正常血糖组,进行各项指标比较;并对手术切除组织标本进行神经相关指标免疫组化染色,观察其表达差异.结果各项指标中,高血糖组更容易出现精神差(P<0.05);有糖尿病史的患者中,血糖得到控制的手术切除率和疼痛出现率明显增高(P<0.05);免疫组化表现,两组亦有差异.结论明确有糖尿病史的胰腺癌患者,积极控制血糖有利于提高根治性手术率,高血糖可使胰腺癌神经发生改变,可能参与了神经浸润的发生.     

Survey on arteriovenous fistula in maintenance hemodialysis patients with type 2 diabetic nephropathy

This paper summed up the characteristics of native arteriovenous fistulas (AVFs) in maintenance hemodialysis patients with type 2 diabetic nephropathy (DN) in Chinese hemodialysis centers. A survey was conducted on AVF in maintenance hemodialysis patients with type 2 DN. A total of 224 cases of maintenance hemodialysis patients were included in this study, among which, 65 cases in DN group, 33 cases in diabetes mellitus (DM) group and 126 cases in non-diabetic control (C) group. Hemoglobin, albumin, blood urea nitrogen, parathyroid hormone and calcium-phosphate product of the three groups of patients were not significantly different. Glycated hemoglobin A1c of DN group and DM group was not significant different. AVF life of (28.7 ± 10.0) months in DN group was significantly shorter than that of (36.5 ± 19.4) months in C group (statistic probability P <0.01), and AVF life of (32.5 ± 10.1) months in DM group (P <0.05) was also shorter than that in C group, while there was no significant difference in AVF life between DN group and DM group. Proportion of upper arm fistula in DN patients (11/65) was significantly higher than that in C group (6/123, P < 0.01). Life of AVF in patients with DN was relatively short, with more times of angioplasty and greater possibility of selecting upper arm internal fistula.     

贡献分析与船舶企业经营决策

在船舶市场竞争激烈和船舶企业经营困难的情况下，本文运用贡献分析理论对企业经营活动进行效益分析，针对订单的选择、亏损船舶是否停产、产品结构的调整等问题提供短期决策框架。     

蒙脱石试验标准化及其质量控制

介绍了按照标准化的要求，对SnCl2容量法在方法精度、稳定性、试剂配制与操作条件进行研究验证，另外在试验全过程利用管理样采取质控图监控蒙脱石测定质量，可用于生产质量监控．     

郑铁一中声屏障工程声学设计研究

声屏障工程是防治铁路噪声影响的有效措施，声学设计是保证声屏障工程降噪效果的重要手段和方法。通过郑铁一中声屏障工程学设计研究，给出了声学设计中应考虑的主要内容及解决方法。声屏障建成后，各主要评价点的实际降噪效果与理论计算值相差不超过1dB；主要评价点的24h等效连续A声级平均降噪量为10.4dB，超过预定目标值2.4dB，降噪效果非常显著。     

Serum renalase inversely related to heart rate variability in dialysis patients

Heart rate variability （HRV） is a noninvasive technique for autonomic nerve activity assessment and an indirect index of adrenergic cardiovascular drive. Renalase is the only known enzyme degrading circulatory catecholamines, participating in regulations of the cardiovascular and sympathetic nervous systems. This study aims at the relation between serum renalase and HRV indexes in dialysis patients. There were 14 hemodialysis （HD） cases, 16 continuous ambulatory peritoneal dialysis （PD） cases, and 16 healthy volunteers enrolled in this study. All the subjects underwent 24 h Holter testing by using a dynamic electocardiogram monitor system to determine HRV parameters, and serum renalase levels were measured. The standard deviation of normal to normal R-R intervals （SDNN, a measure of beat-to-beat variability）, root mean square successive difference （RMSSD）, and the proportion derived by dividing NN50 （the number of interval differences of successive normal to normal intervals greater than 50 ms） by the total number of NN intervals （pNN50） were determined to assess HRV. Both HD and PD patients presented increased maximum heart rate （Max-HR）, minimum heart rate （Min-HR） and average heart rate （Ave-HR）, and presented decreased SDNN, RMSSD and pNN50 relative to healthy controls. Serum levels of renalase were highly negatively correlated with Ave-HR （correlation coefficient r = -0.68, probability P 〈 0.01）, while positively correlated with SDNN （r = 0.64, P 〈 0.01） in both the HD and PD groups. Serum level of renalase was positively correlated with 24 h urine volume （r = 0.73, P 〈 0.01） in PD patients. Renalase might be reciprocally related to HRV and inversely related to Ave-HR in dialysis patients, which will help to probe into renalase＇s physiology and may pave the way to explore renalase replacement therapy in patients with end stage renal disease （ESRD）.     

Serum levels of RBP4 might not be determined by diabetes mellitus but by kidney function and renal replacement therapy

It has been reported that retinol-binding protein 4(RBP4) is associated to adiposity,insulin resistance,and type 2 diabetes.Meanwhile,circulating RBP4 levels are also affected by renal function.The aim of the present study is to investigate whether serum levels of RBP4 are primarily associated with different stages of chronic kidney disease(CKD) or type 2 diabetes,if there is more potential relevance between RBP4 and renal replacement therapy.The serum levels of RBP4 were assessed by commercial competitive enzyme-linked immunosorbent assay(ELISA)kit in 212 patients with the CKD stages 1—5 and in 24 healthy controls,while its correlation with clinical and metabolic parameters was analyzed.The serum level of RBP4 had a strong correlation with estimated glomerular filtration rate(e GFR)(P 0.001).Stratified by e GFR and treatment,no more differences in RBP4 serum concentration were detected between type 2 diabetic and non-diabetic subjects [CKD stages 1—5,non-dialysis(ND),hemodialysis(HD) and peritoneal dialysis(PD);P 0.05 for all].The elevation of RBP4 become higher in HD than in PD and ND in CKD5 patients(P = 0.008 and P = 0.04,respectively),while there was no significant difference between PD and ND groups.Multivariate linear regression analysis demonstrated three independent predictors of e GFR(β =-0.676,P 0.001),C-reactive protein(CRP)(β =-0.573,P 0.001) and creatine(β = 0.509,P = 0.024) in the study population.The study results demonstrated that the serum level of RBP4 was negatively related to the e GFR,whether diabetes mellitus(DM) affected the blood concentration of RBP4 or not.And the serum level of RBP4 exhibited significant difference in different renal replacement therapies.