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Bone morphogenetic protein- 4(BMP- 4) is alow molecular weight glycoprotein ,classified as amorphogen.It is capable of inducing the formationof new cartilage and bone.This osteoinductiveability has led to the use of bone morphogeneticproteins as therapeutic agents for creation of newbone useful in treatment of skeletal injuries anddiseases,and in oral and maxillofacial applica-tions.Although many researchers have got the na-tive BMP from animal s demineralized bone by bio-chemical method,the… 相似文献
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