ACOUSTIC SYSTEMS WITH MULTIPLE INCOHERENT SOURCES AND ITS APPLICATION IN STUDYING NOISES RADIATED FROM VEHICLE ENGINE

ＡＣＯＵＳＴＩＣＳＹＳＴＥＭＳＷＩＴＨＭＵＬＴＩＰＬＥＩＮＣＯＨＥＲＥＮＴＳＯＵＲＣＥＳＡＮＤＩＴＳＡＰＰＬＩＣＡＴＩＯＮＩＮＳＴＵＤＹＩＮＧＮＯＩＳＥＳＲＡＤＩＡＴＥＤＦＲＯＭＶＥＨＩＣＬＥＥＮＧＩＮＥＪｉａｎｇＷｅｉｋａｎｇ（蒋伟康）（Ｓｃｈｏｏ...     

VALUE OF MOTOR EVOKED POTENTIALS BY MAGNETIC STIMULATION IN DIAGNOSIS OF LUMBOSACRAL RADICULOPATHY

ＶＡＬＵＥＯＦＭＯＴＯＲＥＶＯＫＥＤＰＯＴＥＮＴＩＡＬＳＢＹＭＡＧＮＥＴＩＣＳＴＩＭＵＬＡＴＩＯＮＩＮＤＩＡＧＮＯＳＩＳＯＦＬＵＭＢＯＳＡＣＲＡＬＲＡＤＩＣＵＬＯＰＡＴＨＹＹａｎｇＺｈｅ；ＣｈｅｎＪｕｎｃｈａｎｇ；ＺｈａｏＬｏｎｇｚｈｕＷａｎｇＫｕｎ...     

A COMPARATIVE STUDY ON THERAPEUTIC RESPONSE AND SURVIVAL TIME OF PATIENTS WITH MULTIPLE MYELOMA TREATED WITH MODIFIED VMCP RE

ＡＣＯＭＰＡＲＡＴＩＶＥＳＴＵＤＹＯＮＴＨＥＲＡＰＥＵＴＩＣＲＥＳＰＯＮＳＥＡＮＤＳＵＲＶＩＶＡＬＴＩＭＥＯＦＰＡＴＩＥＮＴＳＷＩＴＨ　ＭＵＬＴＩＰＬＥＭＹＥＬＯＭＡＴＲＥＡＴＥＤ　ＷＩＴＨ　ＭＯＤＩＦＩＥＤＶＭＣＰＲＥＧＩＭＥＮＣｈｅｎＸｕｅｍｉｎ...     

AN IMMUNOHISTOCHEMICAL STUDY OF PERIVASCULAR MACROPHAGES IN BRAINS OF SPONTANEOUSLY HYPERTENSIVE RATS

ＡＮＩＭＭＵＮＯＨＩＳＴＯＣＨＥＭＩＣＡＬＳＴＵＤＹＯＦＰＥＲＩＶＡＳＣＵＬＡＲＭＡＣＲＯＰＨＡＧＥＳＩＮＢＲＡＩＮＳＯＦＳＰＯＮＴＡＮＥＯＵＳＬＹＨＹＰＥＲＴＥＮＳＩＶＥ　ＲＡＴＳＬｉｕＹｏｎｇ；ＺｈｏｕＪｉｎｇｄｅ；ＦａｎｇＴａｉｓｈｅｎｇ；Ｌｉ...     

DYNAMIC CHANGES IN Giα2 LEVELS IN THE RAT HEART ASSOCIATED WITH IMPAIRED CARDIAC FUNCTION FOLLOWING ACUTE MYOCARDIAL INFA RCT

ＤＹＮＡＭＩＣＣＨＡＮＧＥＳＩＮＧｉα２ＬＥＶＥＬＳＩＮＴＨＥＲＡＴＨＥＡＲＴＡＳＳＯＣＩＡＴＥＤＷＩＴＨＩＭＰＡＩＲＥＤＣＡＲＤＩＡＣＦＵＮＣＴＩＯＮＦＯＬＬＯＷＩＮＧＡＣＵＴＥＭＹＯＣＡＲＤＩＡＬＩＮＦＡＲＣＴＩＯＮＳｋｉＢｉｎｇ；Ｊ．Ｅ．Ｈｅａ...     

EXISTENCE AND NONUNIQUENESS FOR THE HEAT FLOW OF INHOMOGENEOUS HARMONIC MAP EQUATION

ＥＸＩＳＴＥＮＣＥＡＮＤＮＯＮＵＮＩＱＵＥＮＥＳＳＦＯＲＴＨＥＨＥＡＴＦＬＯＷＯＦＩＮＨＯＭＯＧＥＮＥＯＵＳＨＡＲＭＯＮＩＣＭＡＰＥＱＵＡＴＩＯＮＺｈｏｕＣｈｕｎｑｉｎ（周春琴）（Ｄｅｐｔ．ｏｆＭａｔｈｅｍａｔｉｃｓ，ＳｈａｎｇｈａｉＪｉａｏｔｏｎｇ...     

LOSS OF NUCLEUS BASALIS MAGNOCELLULARIS，BUT NOT SEPTAL，CHOLINERGIC NEURONS CORRELATES WITH PASSIVE AVOIDANCE IMPAIRMENT IN RA

ＬＯＳＳＯＦＮＵＣＬＥＵＳＢＡＳＡＬＩＳＭＡＧＮＯＣＥＬＬＵＬＡＲＩＳ，ＢＵＴＮＯＴＳＥＰＴＡＬ，ＣＨＯＬＩＮＥＲＧＩＣＮＥＵＲＯＮＳ　ＣＯＲＲＥＬＡＴＥＳＷＩＴＨＰＡＳＳＩＶＥＡＶＯＩＤＡＮＣＥＩＭＰＡＩＲＭＥＮＴＩＮＲＡＴＳＴＲＥＡＴＥＤ　ＷＩＴ...     

THE DISTRIBUTION OF ATRIONATRIURETIC POLYPEPTIDE （ANP）－LIKE SUBSTANCE IN THE HEART OF THE HUMAN FETUS AND RAT－AN IMMUNOHISTOC

ＴＨＥＤＩＳＴＲＩＢＵＴＩＯＮＯＦＡＴＲＩＯＮＡＴＲＩＵＲＥＴＩＣＰＯＬＹＰＥＰＴＩＤＥ（ＡＮＰ）－ＬＩＫＥＳＵＢＳＴＡＮＣＥＩＮＴＨＥＨＥＡＲＴＯＦＴＨＥＨＵＭＡＮＦＥＴＵＳＡＮＤＲＡＴ－ＡＮＩＭＭＵＮＯＨＩＳＴＯＣＨＥＭＩＣＡＬＳＴＵＤＹＬｅｉＴ...     

STATIC CORRECTION MODES IN DYNAMICAL SIMULATION OF FLEXIBLE MULTIBODY SYSTEM WITH CLOSED LOOPS

ＳＴＡＴＩＣＣＯＲＲＥＣＴＩＯＮＭＯＤＥＳＩＮＤＹＮＡＭＩＣＡＬＳＩＭＵＬＡＴＩＯＮＯＦＦＬＥＸＩＢＬＥＭＵＬＴＩＢＯＤＹＳＹＳＴＥＭＷＩＴＨＣＬＯＳＥＤＬＯＯＰＳ＊ＹｕＱｉｎｇ（于清）ＨｏｎｇＪｉａｚｈｅｎ（洪嘉振）（Ｄｅｐｔ．ｏｆＥｎｇｉｎｅｅｒ...     

IN SITU IMMUNOHISTOCHEMISTRY STUDY OF INTERCELLULAR ADHESION MOLECULE－1（ICAM－1） IN CHRONIC COLITIS AND COLON CANCER

ＩＮＳＩＴＵＩＭＭＵＮＯＨＩＳＴＯＣＨＥＭＩＳＴＲＹＳＴＵＤＹＯＦＩＮＴＥＲＣＥＬＬＵＬＡＲＡＤＨＥＳＩＯＮＭＯＬＥＣＵＬＥ－１（ＩＣＡＭ－１）ＩＮＣＨＲＯＮＩＣＣＯＬＩＴＩＳ　ＡＮＤ　ＣＯＬＯＮ　ＣＡＮＣＥＲＣｈｅｎＧａｏｐｉｎｇ；ＬｉｕＹｏｎｇ；...     

Value of acoustic perceptual method for analysis of compensatory articulation errors in postoperative patients with cleft palate

Objective To establish an acoustic perceptual method analyzing the compensatory articulation errors in children with operated cleft palate via the formants of Chinese pure vowels. Methods The first three formants which represent vocal transmission character in Chinese pure vowels of 84 subjects with operated cleft palate, were measured by Computerized Speech Signal Processing System （CSSPS）. The Chinese vowel graph of postoperative patients with cleft palate was stated by the first formant frequencies （F1） and the second formant frequencies （F2） of the Chinese pure vowels between the two groups. Results Values of F1 and F2 of vowels except [a] in the poor articulation group （Group A） were significantly different from those in the good articulation group （Group B） （P〈0.05 or P〈 0.01）. As compared with that in Group B, the vowel graph demonstrated the decreased perceptual distances in Group A. These findings indicated that there might still be the backward movements of tongue, perverted mandibular movements and disharmonious lip movements in addition to the velopharyngeal insufficiency （VPI） in Group A. Conclusion The speech articulation of children with repaired cleft palate should be gained by correcting the aberrant compensatory articulation errors in the condition of velopharyngeal competence. Computerized Speech Signal Processing System （CSSPS）, which is regarded us the content of objective quantitative measurement, is a precise, simple, reliable and atroumatic technique for children with cleft palate to analyze pathological compensatory articulation errors.     

以声学元音图评定腭裂术后语音效果的初步研究

对３５例腭裂未手术、３６例腭裂术后患者和１６例正常儿童应用腭裂语音字表测试其语音清晰度；并借助计算机语音分析系统分析其元音共振峰模式。结果表明：腭裂术后组语音清晰度明显高于腭裂未手术组（Ｐ＜０．０１），定量分析了对元音有质的规定性的各元音头三个共振峰频率，利用各元音头两个共振峰绘制出声学元音图，显示腭裂术后感知空间增大。作者认为，声学元音图直观、量化地显示了声学空间与听辨感知相一致的关系，并可作为评价代偿性不良发音习惯存在与否及程度的手段。     

A NEW SPEECH ENHANCEMENT METHOD

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｖａｒｉｏｕｓｓｐｅｅｃｈｐｒｏｃｅｓｉｎｇａｐｐｌｉｃａｔｉｏｎｓ，ｉｔｉｓｖｅｒｙｃｏｍｍｏｎｔｏｆｉｎｄｔｈｅｄｅｇｒａｄａｔｉｏｎｏｆｔｈｅｓｐｅｅｃｈｑｕａｌｉｔｙｃａｕｓｅｄｂｙａｃｏｕｓｔｉｃｂａｃｋｇｒｏｕ...     

腭裂修复术后近期与远期中耳功能的比较研究

为研究腭裂修复术后不同时期的中耳功能状况及其变化趋势。方法　应用声导抗及耳镜检查 ,对 43例术后半年和 2 1例术后 3～ 6年的患者进行中耳功能检测。结果　随着时间的推移 ,术后分泌性中耳炎发生率逐渐下降 ( P <0 .0 5) ,中耳通气功能明显改善 ( P <0 .0 5)。中耳传导系统功能的改善较缓慢。结论　腭裂修复术对咽鼓管 ( ET)及中耳功能的恢复是有益的 ,为临床治疗及进一步的研究提供参考     

ENDPOINT DETECTOR OF NOISY SPEECH SIGNAL USING A RECURRENT NEURAL NETWORK

ＩｎｔｒｏｄｕｃｔｉｏｎＥｎｄｐｏｉｎｔｄｅｔｅｃｔｉｏｎｏｆｓｐｅｅｃｈｓｉｇｎａｌｉｓｉｍｐｏｒｔａｎｔｉｎｍａｎｙａｒｅａｓｏｆｓｐｅｅｃｈｐｒｏｃｅｓｓｉｎｇｔｅｃｈｎｏｌｏｇｙ,ｓｕｃｈａｓｓｐｅｅｃｈｅｎｈａｎｃｅｍｅｎｔ,ｓｐｅｅｃｈｒ...     

SPEECH ENHANCEMENT BASED ON DYNAMIC NOISE ESTIMATION WITHIN AUTO-CORRELATION DOMAIN

IntroductionTo improve the robustness of recognition sys-tems in real environment,many theories and ap-proaches have been brought forward to suppressthe environmental noise ( background noise,chan-nel distortion,etc) ,and they can be divided intothree types according to their thoughts:speech en-hancement,robust feature vector and model com-position. The approach of speech enhancementconsiders extracting clean speech signal fromspeech signal corrupted by noise,typically as SSmethod[1] ( to supp…     

用聚合酶链反应检测口腔癌组织中人乳头状瘤病毒的E_6转化基因

作者采用聚合酶链反应（ＰＣＲ），并对照核酸斑点杂交法对１０例口腔恶性肿瘤组织中ＨＰＶ１６Ｅ６转化基因进行了检测。这些肿瘤包括６例口腔粘膜鳞癌（ＳＣＣ），２例涎腺腺样囊性癌（ＡＣＣ），１例涎腺恶性多形性腺瘤（ＭＰＡ）和１例腭部软组织胚胎性横纹肌肉瘤（ＥＲ）。对照组为１０例非肿瘤组织，包括唇裂、腭裂粘膜组织标本各５例。结果表明两种方法检测结果基本一致，肿瘤组阳性６例（６／１０），包括４例ＳＳＣ，１例ＡＣＣ和１例ＥＲ（除外１例ＡＣＣ用核酸杂交法检测为弱阳性），其余为阴性；对照组用核酸杂交法检测４例，除１例唇裂标本为弱阳性以外，均为阴性（０／４）；用ＰＣＲ法检测１０例均为阴性结果（０／１０）。两组间ＨＰＶ１６Ｅ６转化基因的检出率有明显差异（Ｐ＜０．０５）。这一结果为开展口腔癌的ＨＰＶ病因学研究提供了参考资料。     

ACCURATE SPEECH SEGMENTATION VIA the IMPROVED SHORT-TIME FRACTAL DIMENSION

Thefractalmodeliseffectiveondescribingthenonlinearphenomenainspeechsignalsduetothefactthatthedynamicsofspeechproductionmaycre atesomedegreeofchaos[1 ] .Ithasbeenprovedthatwithinanutterance,thenoise likeconsonantshavehigherfractaldimensionsthanthemoreregularvowels.Thus,speechsignalscanbesegmentedac cordingtothechangesinthefractaldimensiontra jectories[2 ] .Windowsizeandslidingwindowstepareveryimportanttocalculatethefractaldimensiontrajecto ry .Ifthewindowsizeistoolarge ,therelativelyweakerfract…     

SPEECH ENHANCEMENT BASED ON SECOND ORDER ARCHITECTURE AND INFORMATION MAXIMIZATION THEORY

ＣＨＩＴＥＣＴＵＲＥ ＡＮＤ ＩＮＦＯＲＭＡＴＩＯＮ ＭＡＸＩＭＩＺＡＴＩＯＮ ＴＨＥＯＲＹTX＠虞晓＠胡光锐＠陈玮ＩｎｔｒｏｄｕｃｔｉｏｎＴｈｅｂｒｏａｄｕｓｅｏｆｓｐｅｅｃｈｒｅｃｏｇｎｉｔｉｏｎｄｅｍａｎｄｓｅｎ－ｈａｎｃｅｍｅｎｔｏｆｎｏｉｓｙｓｐｅ...     

Enhancing Speech Recognition for Parkinson's Disease Patient Using Transfer Learning Technique

Parkinson's disease patients suffer from disorders of speech.The most frequently reported speech problems are weak,hoarse,nasal or monotonous voice,imprecise articulation,slow or fast speech,difficulty starting speech,impaired stress or rhythm,stuttering,and tremor.To improve the speech quality and assist the patient with speech rehabilitation therapy,we have proposed the speech recognition model for Parkinson's disease patients using transfer learning technique (PSTL),where we have pre-trained the long short-term memory (LSTM)neural network model with our developed publicly available dataset that has been obtained from healthy people through the social media platform.Then,we applied the transfer learning technique to improve the performance of the PSTL framework.The frequency spectrogram masking data augmentation method has been used to alleviate the over-fitting problem so that the word error rate (WER) is further reduced.Even with a limited dataset,our proposed model has effectively reduced the WER from 58％ to 44.5％ on the original speech dataset and 53.1％ to 43％ on the denoised speech dataset,which demonstrated the feasibility of our framework.