REVERSAL OF THE DOUBLE－STRANDED－RNA－INDUCED INHIBITION OF PROTEIN SYNTHESIS BY A CATALYTICALLY INACTIVE MUTANT OF THE PROTEIN

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Modelling minimum-time manoeuvering with global optimisation of local receding horizon control

In this paper, we explore the notion that a human driver uses a receding horizon model predictive control (MPC) scheme for minimum-time manoeuvering. However, MPC is an inherently sub-optimal control scheme because not all future information is incorporated into its finite preview horizon. In many practical applications, this sub-optimality is tolerated as the solution is sufficiently close to optimal. However, it is known that professional drivers have the ability to learn driving circuits and exploit its features to minimise their global manoeuvering time. In this paper, we will model their process with a cascaded optimisation structure. Therein, the inner-loop features a local MPC scheme tasked with finding the control inputs that achieve a blended objective of minimising time and maximising velocity in each preview horizon/distance. The outer loop of this cascaded structure computes the best set of weights for the two components of the local objectives in order to minimise the global manoeuvering time. The proposed cascaded optimisation and control approach is compared against a straight-forward fixed-cost time optimal MPC applied to minimum-time manoeuvering over two well-known race courses. The paper also includes an extended literature review and details of the computational formulation of the model approach.     

Factors Affecting Knowledge,Perceptions, and Attitudes Regarding North Carolina Coastal Reserve Management

During the period May 25–October 28, 2007, we collected data in face-to-face interviews on four sites in the North Carolina Research Reserve system. We subsequently conducted analyses on the effects of education, income, length of visitation, and frequency of visitation on visitor knowledge, perceptions, and attitudes regarding management. Visitors to the sites were well-educated, listed incomes above the state median, and were racially homogeneous. At the overall level, the majority (63%) knew who owned the sites, but only 43% correctly identified the managing agency. The majority also believed that overall conditions at the sites were stable, although those that had been visiting longer perceived conditions as deteriorating. Education was positively correlated with knowledge of ownership and management, and with support for additional rules and enforcement. Neither income, nor frequency of visitation showed any correlation with any of the dependent variables at the overall level. Some site-specific findings differed from the overall findings and varied from site to site. These differences were addressed individually.     

汽车氙灯测试方法：相关性研究

1 背景 在1989年以前,汽车行业没有一个专门的氙灯加速老化测试方法的国际标准.1989年,汽车工程学会(SAE)发布了J1960"水冷式氙灯汽车外饰件加速暴露测试"和SAE J1885"水冷式氙灯汽车内饰件加速暴露测试"两项汽车材料耐候性测试标准.当时,SAE J1960和J1885有利于汽车制造商统一测试条件.但是,这些老化测试标准基于特定型号的设备构造,指定了某生产商的两种型号设备.     

Conservation and development in Oregon's coastal zone

Abstract

Coastal zone management in Oregon is based on the state's general land‐use law. This body of law is designed to deal with population increase, urbanization, and preservation of agricultural land, as well as with other problems throughout the state. Early planning and policy recommendations for the coast were in the hands of a commission having predominantly local membership. This commission produced an extensive series of studies, policies, and recommendations which were assembled as a proposed management tool for natural resources. Staff of the commission was then absorbed into the state land‐management agency, which developed final goals and guidelines for compliance with the Coastal Zone Management Act. Adoption of the coastal goals in December 1976 has triggered deadlines for local government compliance within the coastal zone. The management program is now undergoing federal review.